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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN2
All Species:
4.55
Human Site:
S179
Identified Species:
9.09
UniProt:
P04844
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04844
NP_001129243.1
631
69284
S179
S
Q
Q
A
D
L
R
S
I
V
E
E
I
E
D
Chimpanzee
Pan troglodytes
XP_514629
576
63564
A145
E
T
T
A
L
F
V
A
A
T
Y
K
L
M
D
Rhesus Macaque
Macaca mulatta
XP_001097464
601
65921
A170
T
V
Q
A
L
Q
T
A
S
H
L
S
Q
Q
A
Dog
Lupus familis
XP_865679
631
69015
S179
S
Q
Q
A
D
L
R
S
I
V
E
E
I
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG6
631
69044
N179
S
Q
Q
A
D
L
R
N
I
V
E
E
I
E
D
Rat
Rattus norvegicus
P25235
631
69059
N179
S
Q
Q
A
D
L
R
N
I
V
E
E
I
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006288
631
68881
G180
S
Q
Q
A
D
L
S
G
I
V
E
E
I
E
D
Frog
Xenopus laevis
NP_001079661
631
69212
G179
S
Q
Q
A
N
L
R
G
I
V
E
E
I
E
D
Zebra Danio
Brachydanio rerio
NP_997913
630
68922
E180
A
E
L
G
D
I
L
E
E
I
E
D
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611265
634
69211
A180
A
P
L
L
G
A
S
A
S
F
I
A
N
R
V
Honey Bee
Apis mellifera
XP_395511
673
75606
G207
A
S
D
F
G
T
S
G
M
F
A
F
D
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783899
827
89264
K177
S
N
E
T
N
V
D
K
Y
H
D
L
I
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
94.1
95.8
N.A.
92.3
93.8
N.A.
N.A.
78.1
73.2
66.7
N.A.
33.7
32.6
N.A.
33.3
Protein Similarity:
100
88.9
94.6
98
N.A.
95.4
96
N.A.
N.A.
90.3
86.5
82.7
N.A.
52.2
52
N.A.
49.9
P-Site Identity:
100
13.3
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
13.3
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
53.3
N.A.
13.3
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
67
0
9
0
25
9
0
9
9
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
50
0
9
0
0
0
9
9
9
0
67
% D
% Glu:
9
9
9
0
0
0
0
9
9
0
59
50
0
59
0
% E
% Phe:
0
0
0
9
0
9
0
0
0
17
0
9
0
0
0
% F
% Gly:
0
0
0
9
17
0
0
25
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
50
9
9
0
59
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% K
% Leu:
0
0
17
9
17
50
9
0
0
0
9
9
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
17
0
0
17
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
59
0
0
9
0
0
0
0
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
0
42
0
0
0
0
0
0
17
0
% R
% Ser:
59
9
0
0
0
0
25
17
17
0
0
9
0
0
0
% S
% Thr:
9
9
9
9
0
9
9
0
0
9
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
9
0
0
50
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _