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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN2
All Species:
20.61
Human Site:
S516
Identified Species:
41.21
UniProt:
P04844
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04844
NP_001129243.1
631
69284
S516
E
A
P
S
T
V
L
S
Q
N
L
F
T
P
K
Chimpanzee
Pan troglodytes
XP_514629
576
63564
R468
L
F
R
E
P
E
K
R
P
P
T
V
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001097464
601
65921
K493
I
I
G
D
A
T
L
K
N
P
I
L
W
N
V
Dog
Lupus familis
XP_865679
631
69015
S516
D
A
P
S
T
V
L
S
K
N
L
F
T
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG6
631
69044
S516
E
A
P
S
T
V
L
S
Q
S
L
F
T
P
K
Rat
Rattus norvegicus
P25235
631
69059
S516
E
A
P
S
T
V
L
S
Q
N
L
F
T
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006288
631
68881
S517
D
V
P
S
T
V
Q
S
K
N
L
F
V
P
K
Frog
Xenopus laevis
NP_001079661
631
69212
S516
D
S
P
V
P
I
Q
S
K
N
L
F
I
P
K
Zebra Danio
Brachydanio rerio
NP_997913
630
68922
A514
E
A
P
S
T
I
Q
A
K
T
L
Y
I
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611265
634
69211
P515
N
E
D
K
E
V
K
P
K
N
T
S
G
P
L
Honey Bee
Apis mellifera
XP_395511
673
75606
K558
K
N
V
F
Y
K
S
K
S
N
V
Y
S
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783899
827
89264
A714
E
A
R
P
S
L
P
A
G
S
Q
Y
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
94.1
95.8
N.A.
92.3
93.8
N.A.
N.A.
78.1
73.2
66.7
N.A.
33.7
32.6
N.A.
33.3
Protein Similarity:
100
88.9
94.6
98
N.A.
95.4
96
N.A.
N.A.
90.3
86.5
82.7
N.A.
52.2
52
N.A.
49.9
P-Site Identity:
100
0
6.6
86.6
N.A.
93.3
100
N.A.
N.A.
66.6
46.6
53.3
N.A.
20
13.3
N.A.
13.3
P-Site Similarity:
100
0
13.3
100
N.A.
100
100
N.A.
N.A.
80
73.3
80
N.A.
26.6
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
9
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
42
9
0
9
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
9
0
0
0
0
0
0
0
50
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
17
0
0
0
0
9
0
17
0
0
% I
% Lys:
9
0
0
9
0
9
17
17
42
0
0
0
9
0
67
% K
% Leu:
9
0
0
0
0
9
42
0
0
0
59
9
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
9
59
0
0
0
9
9
% N
% Pro:
0
0
59
9
17
0
9
9
9
17
0
0
0
67
0
% P
% Gln:
0
0
0
0
0
0
25
0
25
0
9
0
0
9
0
% Q
% Arg:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
50
9
0
9
50
9
17
0
9
9
9
0
% S
% Thr:
0
0
0
0
50
9
0
0
0
9
17
0
34
9
0
% T
% Val:
0
9
9
9
0
50
0
0
0
0
9
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _