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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPN2 All Species: 26.06
Human Site: T282 Identified Species: 52.12
UniProt: P04844 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04844 NP_001129243.1 631 69284 T282 P E G S A S D T H E Q A I L R
Chimpanzee Pan troglodytes XP_514629 576 63564 S244 V K L E H A K S V A S R A T V
Rhesus Macaque Macaca mulatta XP_001097464 601 65921 Y269 A V L S H N R Y H V P V V V V
Dog Lupus familis XP_865679 631 69015 T282 P E G T P S D T H E Q A I L R
Cat Felis silvestris
Mouse Mus musculus Q9DBG6 631 69044 T282 P E G S T S D T Q E Q A I L R
Rat Rattus norvegicus P25235 631 69059 T282 P E G S A S D T Q E Q A I L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006288 631 68881 S283 P D G P A A V S H H Q P V L R
Frog Xenopus laevis NP_001079661 631 69212 S282 P D G P A A V S H K Q P L L K
Zebra Danio Brachydanio rerio NP_997913 630 68922 S280 A Q G P A A V S H S Q P F L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611265 634 69211 D285 L I G N G Q L D A Q S P T L N
Honey Bee Apis mellifera XP_395511 673 75606 I312 L A N E E I S I S I Q Q P L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783899 827 89264 T474 L A G P V A V T S A Q P S I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 94.1 95.8 N.A. 92.3 93.8 N.A. N.A. 78.1 73.2 66.7 N.A. 33.7 32.6 N.A. 33.3
Protein Similarity: 100 88.9 94.6 98 N.A. 95.4 96 N.A. N.A. 90.3 86.5 82.7 N.A. 52.2 52 N.A. 49.9
P-Site Identity: 100 0 13.3 86.6 N.A. 86.6 93.3 N.A. N.A. 46.6 40 33.3 N.A. 13.3 13.3 N.A. 20
P-Site Similarity: 100 20 33.3 93.3 N.A. 86.6 93.3 N.A. N.A. 73.3 80 60 N.A. 26.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 0 0 42 42 0 0 9 17 0 34 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 34 9 0 0 0 0 0 0 0 % D
% Glu: 0 34 0 17 9 0 0 0 0 34 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 75 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 50 9 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 9 0 9 0 9 0 0 34 9 0 % I
% Lys: 0 9 0 0 0 0 9 0 0 9 0 0 0 0 9 % K
% Leu: 25 0 17 0 0 0 9 0 0 0 0 0 9 75 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 9 0 0 0 0 0 0 0 0 9 % N
% Pro: 50 0 0 34 9 0 0 0 0 0 9 42 9 0 0 % P
% Gln: 0 9 0 0 0 9 0 0 17 9 75 9 0 0 9 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 42 % R
% Ser: 0 0 0 34 0 34 9 34 17 9 17 0 9 0 9 % S
% Thr: 0 0 0 9 9 0 0 42 0 0 0 0 9 9 0 % T
% Val: 9 9 0 0 9 0 34 0 9 9 0 9 17 9 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _