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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNAI2 All Species: 30.91
Human Site: Y321 Identified Species: 75.56
UniProt: P04899 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04899 NP_002061.1 355 40451 Y321 R K D T K E I Y T H F T C A T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103040 346 39615 E319 N K R K D T K E I Y T H F T C
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P08752 355 40452 Y321 R K D T K E I Y T H F T C A T
Rat Rattus norvegicus P04897 355 40480 Y321 R K D T K E I Y T H F T C A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P50147 355 40559 Y321 R K D T K E I Y T H F T C A T
Frog Xenopus laevis P27044 354 40383 Y320 R K D T K E I Y T H F T C A T
Zebra Danio Brachydanio rerio NP_956136 347 39578 Y313 K K D T K E I Y T H F T C A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20353 355 40577 Y321 R K D Q K E I Y T H L T C A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P51875 354 40433 C321 S A N K E I Y C H M T C A T D
Sea Urchin Strong. purpuratus NP_001001475 354 40273 Y320 R K D Q K E I Y T H F T C A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.8 N.A. N.A. 98 98.5 N.A. N.A. 95.2 88.1 90.1 N.A. 76.6 N.A. 67.6 84.5
Protein Similarity: 100 N.A. 95.7 N.A. N.A. 98.8 99.1 N.A. N.A. 98.3 94 94.3 N.A. 86.7 N.A. 81.6 92.3
P-Site Identity: 100 N.A. 6.6 N.A. N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 86.6 N.A. 0 93.3
P-Site Similarity: 100 N.A. 13.3 N.A. N.A. 100 100 N.A. N.A. 100 100 100 N.A. 86.6 N.A. 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 10 80 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 10 80 0 10 % C
% Asp: 0 0 80 0 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 10 80 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 70 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 80 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 10 80 0 10 0 0 0 0 0 0 % I
% Lys: 10 90 0 20 80 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 70 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 60 0 10 0 0 80 0 20 80 0 20 80 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 80 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _