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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H2AB
All Species:
36.97
Human Site:
T121
Identified Species:
73.94
UniProt:
P04908
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04908
NP_003504.2
130
14135
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Chimpanzee
Pan troglodytes
XP_001137950
130
14103
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001097115
131
14144
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Dog
Lupus familis
XP_545411
130
14147
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P22752
130
14117
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Rat
Rattus norvegicus
P0C170
130
14101
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510088
130
14059
T121
A
V
L
L
P
K
K
T
E
S
H
H
K
A
K
Chicken
Gallus gallus
P02263
129
13922
T121
A
V
L
L
P
K
K
T
D
S
H
K
A
K
A
Frog
Xenopus laevis
P06897
130
13948
T121
S
V
L
L
P
K
K
T
E
S
A
K
S
A
K
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
T121
A
V
L
L
P
K
K
T
G
Q
A
A
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
L116
P
N
I
Q
A
V
L
L
P
K
K
T
E
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
P118
N
I
Q
A
V
L
L
P
K
K
T
S
K
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
97.7
99.2
N.A.
100
99.2
N.A.
97.6
95.3
93
85.2
N.A.
85.3
N.A.
N.A.
87.6
Protein Similarity:
100
99.2
99.2
99.2
N.A.
100
100
N.A.
100
98.4
95.3
88
N.A.
90.7
N.A.
N.A.
91.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
66.6
73.3
53.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
73.3
80
60
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
0
9
9
0
0
0
0
0
17
9
17
75
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
67
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
67
59
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
84
84
0
9
17
9
17
67
17
75
% K
% Leu:
0
0
84
84
0
9
17
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
84
0
0
9
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
75
0
9
9
9
17
% S
% Thr:
0
0
0
0
0
0
0
84
0
0
9
9
0
0
0
% T
% Val:
0
84
0
0
9
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _