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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H2AB All Species: 49.7
Human Site: Y40 Identified Species: 99.39
UniProt: P04908 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04908 NP_003504.2 130 14135 Y40 R L L R K G N Y S E R V G A G
Chimpanzee Pan troglodytes XP_001137950 130 14103 Y40 R L L R K G N Y A E R V G A G
Rhesus Macaque Macaca mulatta XP_001097115 131 14144 Y40 R L L R K G N Y A E R V G A G
Dog Lupus familis XP_545411 130 14147 Y40 R L L R K G N Y S E R V G A G
Cat Felis silvestris
Mouse Mus musculus P22752 130 14117 Y40 R L L R K G N Y S E R V G A G
Rat Rattus norvegicus P0C170 130 14101 Y40 R L L R K G N Y A E R V G A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510088 130 14059 Y40 R L L R K G N Y A E R V G A G
Chicken Gallus gallus P02263 129 13922 Y40 R L L R K G N Y A E R V G A G
Frog Xenopus laevis P06897 130 13948 Y40 R L L R K G N Y A E R V G A G
Zebra Danio Brachydanio rerio Q7ZUY3 142 14983 Y40 R L L R K G N Y A E R V G A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P84051 124 13344 Y39 R L L R K G N Y A E R V G A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P16886 126 13432 Y40 R F L R K G N Y A Q R V G A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 97.7 99.2 N.A. 100 99.2 N.A. 97.6 95.3 93 85.2 N.A. 85.3 N.A. N.A. 87.6
Protein Similarity: 100 99.2 99.2 99.2 N.A. 100 100 N.A. 100 98.4 95.3 88 N.A. 90.7 N.A. N.A. 91.5
P-Site Identity: 100 93.3 93.3 100 N.A. 100 93.3 N.A. 93.3 93.3 93.3 93.3 N.A. 93.3 N.A. N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 75 0 0 0 0 100 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 0 100 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 92 100 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 100 0 0 100 0 0 0 0 0 0 100 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _