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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A2
All Species:
0.61
Human Site:
S219
Identified Species:
1.67
UniProt:
P04920
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04920
NP_003031.3
1241
137009
S219
G
G
D
D
G
G
A
S
G
R
P
L
P
K
A
Chimpanzee
Pan troglodytes
XP_516113
1285
141854
K272
A
S
R
L
A
G
E
K
S
R
P
W
S
P
S
Rhesus Macaque
Macaca mulatta
XP_001103478
1172
130022
L219
V
P
G
V
R
R
H
L
V
R
K
N
A
K
G
Dog
Lupus familis
XP_532761
1223
134633
T219
G
A
S
A
R
P
L
T
K
A
Q
P
G
H
R
Cat
Felis silvestris
Mouse
Mus musculus
P13808
1237
136796
L219
G
G
A
A
G
R
P
L
T
K
A
Q
P
G
H
Rat
Rattus norvegicus
P23347
1234
136617
P219
D
G
G
A
A
G
R
P
L
T
K
A
Q
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
L38
L
G
T
M
S
N
P
L
V
S
D
V
D
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107912
1232
137883
V221
E
H
G
S
I
P
R
V
S
S
R
S
Y
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
H241
M
S
G
G
G
R
H
H
H
S
S
R
K
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.1
92.9
93.1
N.A.
94.1
93.8
N.A.
N.A.
43.4
N.A.
67.1
N.A.
N.A.
N.A.
N.A.
43.8
Protein Similarity:
100
68.8
93.3
94.5
N.A.
95.8
95.5
N.A.
N.A.
55.6
N.A.
79.1
N.A.
N.A.
N.A.
N.A.
59.8
P-Site Identity:
100
20
13.3
6.6
N.A.
26.6
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
13.3
13.3
N.A.
33.3
13.3
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
34
23
0
12
0
0
12
12
12
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
12
0
0
0
0
0
0
12
0
12
12
0
% D
% Glu:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
45
45
12
34
34
0
0
12
0
0
0
12
12
23
% G
% His:
0
12
0
0
0
0
23
12
12
0
0
0
0
23
12
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
12
23
0
12
23
0
% K
% Leu:
12
0
0
12
0
0
12
34
12
0
0
12
0
12
12
% L
% Met:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
12
% N
% Pro:
0
12
0
0
0
23
23
12
0
0
23
12
23
23
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% Q
% Arg:
0
0
12
0
23
34
23
0
0
34
12
12
0
0
12
% R
% Ser:
0
23
12
12
12
0
0
12
23
34
12
12
12
0
12
% S
% Thr:
0
0
12
0
0
0
0
12
12
12
0
0
0
0
0
% T
% Val:
12
0
0
12
0
0
0
12
23
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _