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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A2
All Species:
19.39
Human Site:
S500
Identified Species:
53.33
UniProt:
P04920
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04920
NP_003031.3
1241
137009
S500
A
G
I
T
R
S
K
S
K
H
E
L
K
L
L
Chimpanzee
Pan troglodytes
XP_516113
1285
141854
G553
P
G
G
D
G
H
R
G
K
S
L
K
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001103478
1172
130022
F465
L
S
R
P
T
M
A
F
V
R
L
R
E
A
V
Dog
Lupus familis
XP_532761
1223
134633
S495
A
G
I
T
R
S
K
S
K
H
E
L
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P13808
1237
136796
S496
A
G
I
T
R
S
K
S
K
H
E
L
K
L
L
Rat
Rattus norvegicus
P23347
1234
136617
S497
A
G
I
T
R
S
K
S
K
H
E
L
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
S284
G
P
D
S
P
R
L
S
Y
H
E
I
R
R
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107912
1232
137883
S499
I
G
M
H
R
S
K
S
K
H
E
L
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
K490
S
L
M
K
L
A
H
K
L
D
H
K
K
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.1
92.9
93.1
N.A.
94.1
93.8
N.A.
N.A.
43.4
N.A.
67.1
N.A.
N.A.
N.A.
N.A.
43.8
Protein Similarity:
100
68.8
93.3
94.5
N.A.
95.8
95.5
N.A.
N.A.
55.6
N.A.
79.1
N.A.
N.A.
N.A.
N.A.
59.8
P-Site Identity:
100
20
0
100
N.A.
100
100
N.A.
N.A.
20
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
100
N.A.
N.A.
40
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
0
0
12
12
0
0
0
0
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
67
0
12
0
23
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
12
67
12
0
12
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
12
12
0
0
67
12
0
0
0
0
% H
% Ile:
12
0
45
0
0
0
0
0
0
0
0
12
0
12
0
% I
% Lys:
0
0
0
12
0
0
56
12
67
0
0
23
67
0
0
% K
% Leu:
12
12
0
0
12
0
12
0
12
0
23
56
12
67
56
% L
% Met:
0
0
23
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
12
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
56
12
12
0
0
12
0
12
12
12
0
% R
% Ser:
12
12
0
12
0
56
0
67
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
45
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _