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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC4A2 All Species: 1.21
Human Site: T245 Identified Species: 3.33
UniProt: P04920 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04920 NP_003031.3 1241 137009 T245 R R R I G S M T G A E Q A L L
Chimpanzee Pan troglodytes XP_516113 1285 141854 G298 G S A V G N P G G P E Q Q V P
Rhesus Macaque Macaca mulatta XP_001103478 1172 130022 P245 G P T P R A R P R A P H K P H
Dog Lupus familis XP_532761 1223 134633 A245 S M T G A E Q A L L P R V P T
Cat Felis silvestris
Mouse Mus musculus P13808 1237 136796 Q245 G S M T G V E Q A L L P R V P
Rat Rattus norvegicus P23347 1234 136617 E245 I G S M T G V E Q A L L P R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15575 922 102205 E64 D T Y E G Y V E L H E L V L D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107912 1232 137883 R247 T E Q A K Y Q R I P T D E Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791964 1247 140119 S267 P S G E K N T S P R K K K E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.1 92.9 93.1 N.A. 94.1 93.8 N.A. N.A. 43.4 N.A. 67.1 N.A. N.A. N.A. N.A. 43.8
Protein Similarity: 100 68.8 93.3 94.5 N.A. 95.8 95.5 N.A. N.A. 55.6 N.A. 79.1 N.A. N.A. N.A. N.A. 59.8
P-Site Identity: 100 26.6 6.6 0 N.A. 6.6 6.6 N.A. N.A. 20 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 46.6 13.3 6.6 N.A. 13.3 26.6 N.A. N.A. 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 12 12 0 12 12 34 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % D
% Glu: 0 12 0 23 0 12 12 23 0 0 34 0 12 12 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 12 12 12 45 12 0 12 23 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 12 % H
% Ile: 12 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 23 0 0 0 0 0 12 12 23 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 23 23 23 23 0 23 12 % L
% Met: 0 12 12 12 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 0 12 0 0 12 12 12 23 23 12 12 23 23 % P
% Gln: 0 0 12 0 0 0 23 12 12 0 0 23 12 0 0 % Q
% Arg: 12 12 12 0 12 0 12 12 12 12 0 12 12 12 0 % R
% Ser: 12 34 12 0 0 12 0 12 0 0 0 0 0 0 0 % S
% Thr: 12 12 23 12 12 0 12 12 0 0 12 0 0 0 12 % T
% Val: 0 0 0 12 0 12 23 0 0 0 0 0 23 23 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 23 0 0 0 0 0 0 0 12 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _