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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP1A1 All Species: 35.15
Human Site: S452 Identified Species: 96.67
UniProt: P05023 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05023 NP_000692.2 1023 112896 S452 R A V A G D A S E S A L L K C
Chimpanzee Pan troglodytes XP_513679 1145 126071 S574 R A V A G D A S E S A L L K C
Rhesus Macaque Macaca mulatta XP_001112674 1023 112892 S452 R A V A G D A S E S A L L K C
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VDN2 1023 112964 S452 R A V A G D A S E S A L L K C
Rat Rattus norvegicus P06685 1023 113036 S452 R A V A G D A S E S A L L K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09572 1021 112213 S450 R A V A G D A S E S A L L K C
Frog Xenopus laevis Q92123 1025 113066 S454 R D V A G D A S E S A L L K C
Zebra Danio Brachydanio rerio NP_571764 1024 112442 S453 R D T A G D A S E S A L L K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13607 1041 115586 S470 K E V S G D A S E A A L L K C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 99.7 N.A. N.A. 96.8 96.7 N.A. N.A. 92.5 92 87.6 N.A. 73.9 N.A. N.A. N.A.
Protein Similarity: 100 89.3 100 N.A. N.A. 98.5 98.3 N.A. N.A. 96.3 96.7 94.5 N.A. 86 N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. 73.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 67 0 89 0 0 100 0 0 12 100 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % C
% Asp: 0 23 0 0 0 100 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 100 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 100 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 12 0 0 0 100 0 89 0 0 0 0 0 % S
% Thr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _