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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP1B1 All Species: 24.24
Human Site: Y101 Identified Species: 48.48
UniProt: P05026 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05026 NP_001001787.1 303 35061 Y101 D P K S Y E A Y V L N I V R F
Chimpanzee Pan troglodytes NP_001092025 303 35057 Y101 D P K S Y E A Y V L N I V R F
Rhesus Macaque Macaca mulatta XP_001093541 303 34983 Y101 D P K S Y E A Y V L N I V R F
Dog Lupus familis XP_546597 290 33416 H106 D T E S W D Q H V Q K L N K F
Cat Felis silvestris
Mouse Mus musculus P14094 304 35176 Y101 D P K S Y E A Y V L N I I R F
Rat Rattus norvegicus P07340 304 35183 Y101 D P K S Y E A Y V L N I I R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514227 238 27286 S65 E D C H S S P S D Y I L R G A
Chicken Gallus gallus P08251 305 34922 Y102 D P K S Y D P Y V K N L E G F
Frog Xenopus laevis P21188 277 31552 K98 E I K F S R S K T Q S Y M E Y
Zebra Danio Brachydanio rerio NP_571746 302 35012 Y100 D E V S F L N Y V K V M R E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24046 309 35291 K113 S V I A F D G K K P A E S D Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XUY5 317 35731 Q115 T L I K F N L Q D S K S W E P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 39.9 N.A. 93.7 94.7 N.A. 55.7 70.8 41.5 59.4 N.A. 33.3 N.A. 31.2 N.A.
Protein Similarity: 100 100 99 56.7 N.A. 98 98 N.A. 64.6 85.2 56.7 75.9 N.A. 48.2 N.A. 49.8 N.A.
P-Site Identity: 100 100 100 26.6 N.A. 93.3 93.3 N.A. 0 60 6.6 33.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 100 100 N.A. 13.3 73.3 40 46.6 N.A. 26.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 42 0 0 0 9 0 0 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 9 0 0 0 25 0 0 17 0 0 0 0 9 0 % D
% Glu: 17 9 9 0 0 42 0 0 0 0 0 9 9 25 0 % E
% Phe: 0 0 0 9 25 0 0 0 0 0 0 0 0 0 67 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 17 0 % G
% His: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 17 0 0 0 0 0 0 0 9 42 17 0 0 % I
% Lys: 0 0 59 9 0 0 0 17 9 17 17 0 0 9 0 % K
% Leu: 0 9 0 0 0 9 9 0 0 42 0 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 0 0 50 0 9 0 0 % N
% Pro: 0 50 0 0 0 0 17 0 0 9 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 9 9 0 17 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 17 42 0 % R
% Ser: 9 0 0 67 17 9 9 9 0 9 9 9 9 0 0 % S
% Thr: 9 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % T
% Val: 0 9 9 0 0 0 0 0 67 0 9 0 25 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 50 0 0 59 0 9 0 9 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _