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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHGB
All Species:
8.48
Human Site:
S259
Identified Species:
20.74
UniProt:
P05060
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05060
NP_001810.2
677
78246
S259
E
S
K
G
Q
P
R
S
Q
E
E
S
E
E
G
Chimpanzee
Pan troglodytes
XP_525418
756
86471
S338
E
S
K
G
Q
P
R
S
Q
E
E
S
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001112965
759
87072
S341
E
S
K
G
Q
P
G
S
Q
E
E
S
E
E
S
Dog
Lupus familis
XP_534354
668
77037
E259
G
S
R
E
E
S
E
E
S
E
E
D
T
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P16014
677
77950
G266
E
S
Q
E
G
E
E
G
E
E
G
E
E
G
E
Rat
Rattus norvegicus
O35314
675
77517
E258
D
Q
D
Q
S
E
E
E
S
E
E
G
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514396
644
76719
R270
R
A
R
F
W
D
K
R
G
H
H
K
K
N
Y
Chicken
Gallus gallus
XP_419377
673
79084
K270
E
K
K
S
Y
K
P
K
R
Y
H
G
K
H
R
Frog
Xenopus laevis
NP_001088193
438
49611
N74
I
S
I
L
R
H
Q
N
L
L
K
E
L
Q
E
Zebra Danio
Brachydanio rerio
Q5RG44
1079
123596
E331
A
E
K
R
R
I
Q
E
L
Q
E
K
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
83.5
73.1
N.A.
62.9
64.1
N.A.
37.3
35.1
23
20
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
85.2
81.6
N.A.
75
76.9
N.A.
52.8
54.3
40.3
33.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
20
N.A.
26.6
33.3
N.A.
0
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
40
N.A.
40
40
N.A.
26.6
26.6
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
10
0
0
0
0
0
10
0
10
0
% D
% Glu:
50
10
0
20
10
20
30
30
10
60
60
20
50
40
20
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
30
10
0
10
10
10
0
10
20
0
10
30
% G
% His:
0
0
0
0
0
10
0
0
0
10
20
0
0
10
0
% H
% Ile:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
50
0
0
10
10
10
0
0
10
20
20
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
20
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
30
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
10
10
10
30
0
20
0
30
10
0
0
0
10
0
% Q
% Arg:
10
0
20
10
20
0
20
10
10
0
0
0
10
0
20
% R
% Ser:
0
60
0
10
10
10
0
30
20
0
0
30
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _