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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDOB All Species: 53.03
Human Site: S272 Identified Species: 89.74
UniProt: P05062 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05062 NP_000026.2 364 39473 S272 V P G I C F L S G G M S E E D
Chimpanzee Pan troglodytes Q5R1X4 364 39508 S272 V P G V T F L S G G Q S E E E
Rhesus Macaque Macaca mulatta XP_001111095 364 39445 S272 V P G I C F L S G G M S E E D
Dog Lupus familis XP_532017 364 39633 S272 V P G I C F L S G G M S E E D
Cat Felis silvestris
Mouse Mus musculus Q91Y97 364 39488 S272 V P G I C F L S G G M S E E D
Rat Rattus norvegicus P00884 364 39600 S272 V P S I C F L S G G M S E E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511857 364 39520 S272 V P G I C F L S G G M S E E D
Chicken Gallus gallus P07341 364 39277 S272 V P G I C F L S G G Q S E E E
Frog Xenopus laevis NP_001079567 364 39420 S272 V P G I C F L S G G Q S E E E
Zebra Danio Brachydanio rerio Q8JH71 364 39269 S272 V P G I C F L S G G Q S E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07764 361 39029 S271 V T G V T F L S G G Q S E E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46563 366 38828 S275 V P G I T F L S G G Q S E L D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P08440 355 38586 S266 V P A V L F L S G G Q S E E E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P22197 358 38792 S266 I P G I V F L S G I Q R E E Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.4 99.1 91.7 N.A. 95.8 95.3 N.A. 90.1 80.7 72.8 76 N.A. 64.5 N.A. 59.8 N.A.
Protein Similarity: 100 82.1 99.7 95.5 N.A. 98.6 98.3 N.A. 95.3 88.1 83.7 86.8 N.A. 75 N.A. 71.3 N.A.
P-Site Identity: 100 73.3 100 100 N.A. 100 93.3 N.A. 100 86.6 86.6 86.6 N.A. 66.6 N.A. 80 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 93.3 N.A. 80 N.A. 80 N.A.
Percent
Protein Identity: N.A. 57.6 N.A. 54.6 N.A. N.A.
Protein Similarity: N.A. 67.5 N.A. 66.2 N.A. N.A.
P-Site Identity: N.A. 66.6 N.A. 60 N.A. N.A.
P-Site Similarity: N.A. 80 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 100 93 43 % E
% Phe: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 86 0 0 0 0 0 100 93 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 79 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 100 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 58 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 100 0 0 0 93 0 0 0 % S
% Thr: 0 8 0 0 22 0 0 0 0 0 0 0 0 0 0 % T
% Val: 93 0 0 22 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _