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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH2
All Species:
33.64
Human Site:
Y149
Identified Species:
56.92
UniProt:
P05091
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05091
NP_000681.2
517
56381
Y149
V
L
K
C
L
R
Y
Y
A
G
W
A
D
K
Y
Chimpanzee
Pan troglodytes
XP_509379
517
55884
Y149
V
L
K
C
L
R
Y
Y
A
G
W
A
D
K
Y
Rhesus Macaque
Macaca mulatta
XP_001114412
517
57157
F149
V
I
K
V
Y
R
Y
F
A
G
W
A
D
K
W
Dog
Lupus familis
XP_853628
521
56744
Y153
V
L
R
C
L
R
Y
Y
A
G
W
A
D
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P47738
519
56519
Y151
V
L
K
C
L
R
Y
Y
A
G
W
A
D
K
Y
Rat
Rattus norvegicus
P11884
519
56470
Y151
V
L
K
C
L
R
Y
Y
A
G
W
A
D
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506461
571
62215
H203
V
V
K
C
L
R
Y
H
A
G
W
A
D
K
Y
Chicken
Gallus gallus
P27463
509
55791
C141
C
I
K
T
I
R
Y
C
A
G
W
A
D
K
I
Frog
Xenopus laevis
NP_001087022
521
57231
Y153
V
L
K
C
L
R
Y
Y
A
G
W
A
D
K
C
Zebra Danio
Brachydanio rerio
NP_956784
516
56547
Y148
V
V
K
C
L
R
Y
Y
A
G
W
A
D
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609285
520
57001
F152
A
I
K
N
L
R
Y
F
A
G
W
A
D
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786787
525
56894
F157
V
L
A
T
L
R
Y
F
A
G
W
A
D
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
Y169
F
A
R
L
F
R
Y
Y
A
G
W
A
D
K
I
Baker's Yeast
Sacchar. cerevisiae
P32872
511
56448
T154
V
L
K
E
L
R
Y
T
A
G
W
A
D
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.6
72.5
93.6
N.A.
94.9
95.5
N.A.
79.8
66.5
79.4
78.3
N.A.
69.4
N.A.
N.A.
66.6
Protein Similarity:
100
83.7
84.3
97.3
N.A.
97.1
97.6
N.A.
84.7
79.8
88.6
88.9
N.A.
81.1
N.A.
N.A.
81.5
P-Site Identity:
100
100
66.6
93.3
N.A.
100
100
N.A.
86.6
60
93.3
86.6
N.A.
66.6
N.A.
N.A.
73.3
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
73.3
93.3
100
N.A.
80
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.3
56.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.4
67.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
0
100
0
0
100
0
0
0
% A
% Cys:
8
0
0
58
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
8
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
22
0
0
8
0
0
0
0
0
0
0
0
0
22
% I
% Lys:
0
0
79
0
0
0
0
0
0
0
0
0
0
100
0
% K
% Leu:
0
58
0
8
79
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
79
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
15
% W
% Tyr:
0
0
0
0
8
0
100
58
0
0
0
0
0
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _