KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH2
All Species:
48.48
Human Site:
Y442
Identified Species:
82.05
UniProt:
P05091
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05091
NP_000681.2
517
56381
Y442
G
R
A
N
N
S
T
Y
G
L
A
A
A
V
F
Chimpanzee
Pan troglodytes
XP_509379
517
55884
Y442
G
R
A
N
N
S
T
Y
G
L
A
A
A
V
F
Rhesus Macaque
Macaca mulatta
XP_001114412
517
57157
Y442
E
R
A
N
N
T
R
Y
G
L
A
A
A
V
F
Dog
Lupus familis
XP_853628
521
56744
Y446
G
R
A
N
N
S
K
Y
G
L
A
A
A
V
F
Cat
Felis silvestris
Mouse
Mus musculus
P47738
519
56519
Y444
G
R
A
N
D
S
K
Y
G
L
A
A
A
V
F
Rat
Rattus norvegicus
P11884
519
56470
Y444
G
R
A
N
N
S
K
Y
G
L
A
A
A
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506461
571
62215
Y496
E
R
A
N
N
S
K
Y
G
L
A
A
A
V
F
Chicken
Gallus gallus
P27463
509
55791
Y434
K
R
A
N
N
T
T
Y
G
L
A
A
A
V
F
Frog
Xenopus laevis
NP_001087022
521
57231
Y446
D
R
A
N
N
S
M
Y
G
L
A
A
A
V
F
Zebra Danio
Brachydanio rerio
NP_956784
516
56547
Y441
E
R
A
N
D
S
K
Y
G
L
A
A
A
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609285
520
57001
Y445
E
R
A
N
N
S
E
Y
G
L
A
A
A
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786787
525
56894
Y450
N
R
A
N
N
T
E
Y
G
L
A
A
A
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
Y462
K
R
A
N
E
T
K
Y
G
L
A
A
G
V
F
Baker's Yeast
Sacchar. cerevisiae
P32872
511
56448
I435
E
E
I
F
G
P
V
I
T
I
S
R
F
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.6
72.5
93.6
N.A.
94.9
95.5
N.A.
79.8
66.5
79.4
78.3
N.A.
69.4
N.A.
N.A.
66.6
Protein Similarity:
100
83.7
84.3
97.3
N.A.
97.1
97.6
N.A.
84.7
79.8
88.6
88.9
N.A.
81.1
N.A.
N.A.
81.5
P-Site Identity:
100
100
80
93.3
N.A.
86.6
93.3
N.A.
86.6
86.6
86.6
80
N.A.
86.6
N.A.
N.A.
80
P-Site Similarity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
86.6
93.3
86.6
86.6
N.A.
86.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.3
56.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.4
67.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
93
0
0
0
0
0
0
0
93
93
86
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
36
8
0
0
8
0
15
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
93
% F
% Gly:
36
0
0
0
8
0
0
0
93
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
15
0
0
0
0
0
43
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
93
72
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
93
0
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
65
0
0
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
29
22
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
93
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _