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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP17A1
All Species:
17.58
Human Site:
T73
Identified Species:
38.67
UniProt:
P05093
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05093
NP_000093.1
508
57371
T73
V
R
M
G
T
K
T
T
V
I
V
G
H
H
Q
Chimpanzee
Pan troglodytes
Q8HYN1
508
57365
T73
V
R
M
G
T
K
T
T
V
I
V
G
H
H
Q
Rhesus Macaque
Macaca mulatta
Q8HYM9
508
57600
T73
V
R
M
G
T
K
T
T
V
I
V
G
H
H
Q
Dog
Lupus familis
XP_851226
511
57803
T73
F
R
M
G
T
K
T
T
V
M
V
G
H
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
P27786
507
57619
A73
L
R
L
G
T
T
T
A
V
I
V
G
H
Y
Q
Rat
Rattus norvegicus
P11715
507
57232
T73
L
R
L
G
T
T
T
T
V
I
I
G
H
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P12394
508
56966
V78
L
W
M
G
S
H
Y
V
V
V
V
N
S
Y
Q
Frog
Xenopus laevis
NP_001090540
511
57749
I79
F
R
M
G
S
H
Y
I
V
I
V
N
H
H
E
Zebra Danio
Brachydanio rerio
NP_997971
519
58317
L86
L
M
M
G
S
H
K
L
L
I
V
N
N
H
H
Tiger Blowfish
Takifugu rubipres
NP_001098706
517
57319
V79
L
M
M
G
S
H
R
V
I
I
V
N
H
H
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789963
507
57031
M86
F
K
A
G
E
R
W
M
V
V
L
N
R
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.4
78.4
N.A.
66.7
68.3
N.A.
N.A.
48.4
48.9
48.9
48.1
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
100
96.6
90
N.A.
81.3
82
N.A.
N.A.
69.2
67.3
66.4
64.9
N.A.
N.A.
N.A.
52.5
P-Site Identity:
100
100
100
86.6
N.A.
66.6
66.6
N.A.
N.A.
33.3
53.3
33.3
40
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
60
66.6
60
60
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
100
0
0
0
0
0
0
0
55
0
0
0
% G
% His:
0
0
0
0
0
37
0
0
0
0
0
0
73
64
10
% H
% Ile:
0
0
0
0
0
0
0
10
10
73
10
0
0
0
0
% I
% Lys:
0
10
0
0
0
37
10
0
0
0
0
0
0
0
0
% K
% Leu:
46
0
19
0
0
0
0
10
10
0
10
0
0
0
0
% L
% Met:
0
19
73
0
0
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
46
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
64
% Q
% Arg:
0
64
0
0
0
10
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
37
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
55
19
55
46
0
0
0
0
0
0
0
% T
% Val:
28
0
0
0
0
0
0
19
82
19
82
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
0
0
0
0
0
0
28
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _