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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP11A1
All Species:
6.06
Human Site:
S491
Identified Species:
13.33
UniProt:
P05108
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05108
NP_000772.2
521
60102
S491
R
V
E
I
Q
H
L
S
D
V
G
T
T
F
N
Chimpanzee
Pan troglodytes
XP_001164690
433
49697
D404
V
E
I
Q
H
L
S
D
V
G
T
T
F
N
L
Rhesus Macaque
Macaca mulatta
XP_001096506
461
53206
S431
R
V
E
I
Q
H
L
S
D
V
G
T
T
F
N
Dog
Lupus familis
XP_535539
520
60210
R490
R
V
E
M
Q
Q
L
R
D
V
G
T
T
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ82
526
60296
R487
R
I
E
V
Q
N
L
R
D
V
G
T
K
F
S
Rat
Rattus norvegicus
P14137
526
60567
R488
R
I
E
V
Q
S
I
R
D
V
G
T
K
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512763
496
56138
V466
H
I
L
K
N
F
Q
V
E
T
V
S
R
E
D
Chicken
Gallus gallus
NP_001001756
508
58177
R479
N
F
K
I
E
T
K
R
A
V
E
V
G
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691817
512
58818
R483
N
F
R
I
E
K
Q
R
Q
M
E
V
K
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR9
524
60579
H492
A
N
L
V
R
N
F
H
I
E
Y
N
Y
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09660
489
56052
Y459
L
A
K
L
C
G
N
Y
D
I
R
H
R
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
84.2
79.8
N.A.
74.9
76
N.A.
38.3
51
N.A.
47
N.A.
28.2
N.A.
26.8
N.A.
Protein Similarity:
100
76.3
85.9
89.6
N.A.
85.3
86.3
N.A.
54.1
69
N.A.
67.3
N.A.
46.5
N.A.
46
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
60
60
N.A.
0
13.3
N.A.
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
100
86.6
N.A.
86.6
80
N.A.
26.6
26.6
N.A.
20
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
55
0
0
0
0
0
19
% D
% Glu:
0
10
46
0
19
0
0
0
10
10
19
0
0
10
0
% E
% Phe:
0
19
0
0
0
10
10
0
0
0
0
0
10
46
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
46
0
10
10
0
% G
% His:
10
0
0
0
10
19
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
28
10
37
0
0
10
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
19
10
0
10
10
0
0
0
0
0
28
0
10
% K
% Leu:
10
0
19
10
0
10
37
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
19
10
0
0
10
19
10
0
0
0
0
10
0
10
37
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
46
10
19
0
10
0
0
0
0
0
0
% Q
% Arg:
46
0
10
0
10
0
0
46
0
0
10
0
19
0
0
% R
% Ser:
0
0
0
0
0
10
10
19
0
0
0
10
0
19
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
10
55
28
10
10
% T
% Val:
10
28
0
28
0
0
0
10
10
55
10
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _