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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL4
All Species:
14.55
Human Site:
T142
Identified Species:
64
UniProt:
P05112
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05112
NP_000580.1
153
17492
T142
N
F
L
E
R
L
K
T
I
M
R
E
K
Y
S
Chimpanzee
Pan troglodytes
NP_001011714
153
17504
T142
N
F
L
E
R
L
K
T
I
M
R
E
K
Y
S
Rhesus Macaque
Macaca mulatta
P51492
153
17433
T142
D
F
L
E
R
L
K
T
I
M
R
E
K
Y
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P07750
140
15815
S130
S
L
K
D
F
L
E
S
L
K
S
I
M
Q
M
Rat
Rattus norvegicus
P20096
147
16228
S133
D
F
L
E
S
L
K
S
I
L
R
G
K
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007080
136
14798
R126
E
K
F
L
A
D
L
R
T
F
F
H
Q
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.4
N.A.
N.A.
41.8
45
N.A.
N.A.
26.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.7
N.A.
N.A.
57.5
60.7
N.A.
N.A.
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
6.6
60
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
40
80
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
17
0
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
67
0
0
17
0
0
0
0
50
0
0
0
% E
% Phe:
0
67
17
0
17
0
0
0
0
17
17
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
67
0
0
17
0
0
0
% I
% Lys:
0
17
17
0
0
0
67
0
0
17
0
0
67
0
0
% K
% Leu:
0
17
67
17
0
84
17
0
17
17
0
0
0
17
17
% L
% Met:
0
0
0
0
0
0
0
0
0
50
0
0
17
0
17
% M
% Asn:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
17
17
0
% Q
% Arg:
0
0
0
0
50
0
0
17
0
0
67
0
0
0
0
% R
% Ser:
17
0
0
0
17
0
0
34
0
0
17
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
50
17
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _