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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCG
All Species:
33.03
Human Site:
S241
Identified Species:
66.06
UniProt:
P05129
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05129
NP_002730.1
697
78448
S241
G
D
V
E
R
R
L
S
V
E
V
W
D
W
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116809
695
78118
S239
G
D
V
E
R
R
L
S
V
E
V
W
D
W
D
Dog
Lupus familis
XP_541432
673
75218
Q241
S
E
E
E
T
Q
T
Q
R
D
T
E
T
E
C
Cat
Felis silvestris
Mouse
Mus musculus
P20444
672
76833
S241
S
D
K
D
R
R
L
S
V
E
I
W
D
W
D
Rat
Rattus norvegicus
P63319
697
78339
S241
G
D
V
E
R
R
L
S
V
E
V
W
D
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510097
675
76844
S242
T
D
K
D
R
R
L
S
V
E
I
W
D
W
D
Chicken
Gallus gallus
NP_001012822
674
76827
S241
T
D
K
D
R
R
L
S
V
E
V
W
D
W
D
Frog
Xenopus laevis
Q7LZQ8
671
76506
S238
S
D
K
D
R
R
L
S
V
E
I
W
D
W
E
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
S240
S
D
K
D
R
R
L
S
V
E
I
W
D
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05130
679
77676
L259
E
D
K
D
R
R
I
L
I
E
V
W
D
W
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90980
682
77982
S244
G
D
K
D
R
R
L
S
I
E
V
W
D
W
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R707
G
Y
G
R
P
D
S
R
D
D
E
Y
S
A
Q
Conservation
Percent
Protein Identity:
100
N.A.
95.5
91.2
N.A.
68.5
99
N.A.
69.8
69.7
66.7
68.1
N.A.
62.1
N.A.
60.6
N.A.
Protein Similarity:
100
N.A.
96.8
92.4
N.A.
81
99.5
N.A.
82.3
81.4
79
80.6
N.A.
75.1
N.A.
74.6
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
73.3
100
N.A.
73.3
80
66.6
73.3
N.A.
60
N.A.
80
N.A.
P-Site Similarity:
100
N.A.
100
26.6
N.A.
86.6
100
N.A.
86.6
86.6
86.6
86.6
N.A.
80
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
84
0
59
0
9
0
0
9
17
0
0
84
0
75
% D
% Glu:
9
9
9
34
0
0
0
0
0
84
9
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
17
0
34
0
0
0
0
% I
% Lys:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
75
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
9
84
84
0
9
9
0
0
0
0
0
0
% R
% Ser:
34
0
0
0
0
0
9
75
0
0
0
0
9
0
0
% S
% Thr:
17
0
0
0
9
0
9
0
0
0
9
0
9
0
0
% T
% Val:
0
0
25
0
0
0
0
0
67
0
50
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
84
0
84
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _