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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCG All Species: 13.94
Human Site: S321 Identified Species: 27.88
UniProt: P05129 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05129 NP_002730.1 697 78448 S321 R V R M G P S S S P I P S P S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116809 695 78118 S319 R V R M G P S S S P I P S P S
Dog Lupus familis XP_541432 673 75218 R321 F F G T S P G R L H I S D F S
Cat Felis silvestris
Mouse Mus musculus P20444 672 76833 S321 G N K V I S P S E D R K Q P S
Rat Rattus norvegicus P63319 697 78339 S321 R V R M G P S S S P I P S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510097 675 76844 S322 G N K V I G P S E D R K S S V
Chicken Gallus gallus NP_001012822 674 76827 S321 G N K V I T P S E D R N S S V
Frog Xenopus laevis Q7LZQ8 671 76506 G318 N K A A G R E G G K P S V Q G
Zebra Danio Brachydanio rerio Q7SY24 670 76288 N320 K T D G S S S N A I S K F D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05130 679 77676 S339 S D T N T H T S S K K D M I R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90980 682 77982 D324 N S S S K P K D P A A P R A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P87253 1142 127954 P787 S Y D N Q V V P S A S G V P V
Conservation
Percent
Protein Identity: 100 N.A. 95.5 91.2 N.A. 68.5 99 N.A. 69.8 69.7 66.7 68.1 N.A. 62.1 N.A. 60.6 N.A.
Protein Similarity: 100 N.A. 96.8 92.4 N.A. 81 99.5 N.A. 82.3 81.4 79 80.6 N.A. 75.1 N.A. 74.6 N.A.
P-Site Identity: 100 N.A. 100 20 N.A. 20 100 N.A. 13.3 13.3 6.6 13.3 N.A. 13.3 N.A. 20 N.A.
P-Site Similarity: 100 N.A. 100 20 N.A. 33.3 100 N.A. 26.6 26.6 6.6 33.3 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 25.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 38
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 9 17 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 17 0 0 0 0 9 0 25 0 9 9 9 0 % D
% Glu: 0 0 0 0 0 0 9 0 25 0 0 0 0 0 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 9 9 0 % F
% Gly: 25 0 9 9 34 9 9 9 9 0 0 9 0 0 9 % G
% His: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 25 0 0 0 0 9 34 0 0 9 0 % I
% Lys: 9 9 25 0 9 0 9 0 0 17 9 25 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 25 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 17 25 0 17 0 0 0 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 42 25 9 9 25 9 34 0 42 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 9 9 0 % Q
% Arg: 25 0 25 0 0 9 0 9 0 0 25 0 9 0 9 % R
% Ser: 17 9 9 9 17 17 34 59 42 0 17 17 42 17 59 % S
% Thr: 0 9 9 9 9 9 9 0 0 0 0 0 0 0 0 % T
% Val: 0 25 0 25 0 9 9 0 0 0 0 0 17 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _