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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A5 All Species: 35.45
Human Site: S42 Identified Species: 60
UniProt: P05141 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05141 NP_001143.2 298 32895 S42 L L Q V Q H A S K Q I T A D K
Chimpanzee Pan troglodytes XP_517556 500 54130 S244 L L Q V Q H A S K Q I S A E K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851701 298 32999 S42 L L Q V Q H A S K Q I T A D K
Cat Felis silvestris
Mouse Mus musculus P51881 298 32913 S42 L L Q V Q H A S K Q I T A D K
Rat Rattus norvegicus Q09073 298 32883 S42 L L Q V Q H A S K Q I T A D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989562 298 32730 S42 L L Q V Q H A S K Q I A A D K
Frog Xenopus laevis Q7ZY36 473 52338 E186 T I P D E F T E E E K K T G Q
Zebra Danio Brachydanio rerio NP_775354 298 32745 S42 L L Q V Q H A S K Q I T A D K
Tiger Blowfish Takifugu rubipres NP_001037838 298 32796 S42 L L Q V Q H A S K Q I T A D K
Fruit Fly Dros. melanogaster Q26365 312 34196 S57 L L Q V Q H I S K Q I S P D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P04709 387 42373 I122 I Q N Q D E M I K S G R L S E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P40941 385 41727 L119 I Q N Q D E M L K A G R L T E
Baker's Yeast Sacchar. cerevisiae P18238 307 33294 I47 I Q N Q D E M I K Q G T L D K
Red Bread Mold Neurospora crassa P02723 313 33870 I48 V Q N Q D E M I R A G R L D R
Conservation
Percent
Protein Identity: 100 53.5 N.A. 97.6 N.A. 98.6 98.9 N.A. N.A. 92.9 22.2 92.6 92.2 77.5 N.A. N.A. N.A.
Protein Similarity: 100 56.7 N.A. 98.9 N.A. 99.3 99.6 N.A. N.A. 95.9 36.7 96.9 96.3 83.9 N.A. N.A. N.A.
P-Site Identity: 100 86.6 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 0 100 100 80 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 33.3 100 100 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 43.6 N.A. 43.9 54 50.1
Protein Similarity: N.A. 53.7 N.A. 54 68 64.8
P-Site Identity: N.A. 6.6 N.A. 6.6 33.3 6.6
P-Site Similarity: N.A. 20 N.A. 20 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 58 0 0 15 0 8 58 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 29 0 0 0 0 0 0 0 0 72 0 % D
% Glu: 0 0 0 0 8 29 0 8 8 8 0 0 0 8 15 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 29 0 0 8 0 % G
% His: 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 8 0 0 0 0 8 22 0 0 65 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 86 0 8 8 0 0 72 % K
% Leu: 65 65 0 0 0 0 0 8 0 0 0 0 29 0 0 % L
% Met: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 29 65 29 65 0 0 0 0 72 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 22 0 0 8 % R
% Ser: 0 0 0 0 0 0 0 65 0 8 0 15 0 8 0 % S
% Thr: 8 0 0 0 0 0 8 0 0 0 0 50 8 8 0 % T
% Val: 8 0 0 65 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _