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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A5
All Species:
33.64
Human Site:
T254
Identified Species:
56.92
UniProt:
P05141
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05141
NP_001143.2
298
32895
T254
T
D
I
M
Y
T
G
T
L
D
C
W
R
K
I
Chimpanzee
Pan troglodytes
XP_517556
500
54130
T456
A
D
I
M
Y
T
G
T
V
D
C
W
R
K
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851701
298
32999
T254
T
D
I
M
Y
T
G
T
L
D
C
W
R
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P51881
298
32913
T254
T
D
I
M
Y
T
G
T
L
D
C
W
R
K
I
Rat
Rattus norvegicus
Q09073
298
32883
T254
T
D
I
M
Y
T
G
T
L
D
C
W
R
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989562
298
32730
T254
A
D
I
M
Y
S
G
T
I
D
C
W
R
K
I
Frog
Xenopus laevis
Q7ZY36
473
52338
Q423
A
S
I
E
G
A
P
Q
L
N
M
G
G
L
F
Zebra Danio
Brachydanio rerio
NP_775354
298
32745
T254
A
D
I
M
Y
S
G
T
I
D
C
W
R
K
I
Tiger Blowfish
Takifugu rubipres
NP_001037838
298
32796
T254
A
E
I
M
Y
T
G
T
I
D
C
W
R
K
I
Fruit Fly
Dros. melanogaster
Q26365
312
34196
T268
T
E
V
I
Y
K
N
T
L
H
C
W
A
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
D335
V
K
Y
K
S
S
L
D
A
F
Q
Q
I
L
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
D333
V
K
Y
K
S
S
F
D
A
F
S
Q
I
V
K
Baker's Yeast
Sacchar. cerevisiae
P18238
307
33294
D259
V
K
Y
N
G
A
I
D
C
L
K
K
I
V
A
Red Bread Mold
Neurospora crassa
P02723
313
33870
D261
V
K
Y
K
S
S
F
D
A
A
S
Q
I
V
A
Conservation
Percent
Protein Identity:
100
53.5
N.A.
97.6
N.A.
98.6
98.9
N.A.
N.A.
92.9
22.2
92.6
92.2
77.5
N.A.
N.A.
N.A.
Protein Similarity:
100
56.7
N.A.
98.9
N.A.
99.3
99.6
N.A.
N.A.
95.9
36.7
96.9
96.3
83.9
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
N.A.
100
N.A.
100
100
N.A.
N.A.
80
13.3
80
80
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
20
93.3
93.3
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
43.6
N.A.
43.9
54
50.1
Protein Similarity:
N.A.
53.7
N.A.
54
68
64.8
P-Site Identity:
N.A.
0
N.A.
0
0
0
P-Site Similarity:
N.A.
6.6
N.A.
6.6
0
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
0
0
0
15
0
0
22
8
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
65
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
29
0
58
0
0
0
0
0
% D
% Glu:
0
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
15
0
0
0
0
8
% F
% Gly:
0
0
0
0
15
0
58
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
65
8
0
0
8
0
22
0
0
0
29
0
65
% I
% Lys:
0
29
0
22
0
8
0
0
0
0
8
8
0
58
15
% K
% Leu:
0
0
0
0
0
0
8
0
43
8
0
0
0
15
0
% L
% Met:
0
0
0
58
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
22
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% R
% Ser:
0
8
0
0
22
36
0
0
0
0
15
0
0
0
0
% S
% Thr:
36
0
0
0
0
43
0
65
0
0
0
0
0
8
0
% T
% Val:
29
0
8
0
0
0
0
0
8
0
0
0
0
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
0
% W
% Tyr:
0
0
29
0
65
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _