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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A5
All Species:
50.61
Human Site:
Y191
Identified Species:
85.64
UniProt:
P05141
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05141
NP_001143.2
298
32895
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Chimpanzee
Pan troglodytes
XP_517556
500
54130
Y393
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851701
298
32999
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P51881
298
32913
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Rat
Rattus norvegicus
Q09073
298
32883
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989562
298
32730
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Frog
Xenopus laevis
Q7ZY36
473
52338
D360
I
I
P
Y
A
G
I
D
L
A
I
Y
E
T
L
Zebra Danio
Brachydanio rerio
NP_775354
298
32745
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Tiger Blowfish
Takifugu rubipres
NP_001037838
298
32796
Y191
I
I
I
Y
R
A
A
Y
F
G
I
Y
D
T
A
Fruit Fly
Dros. melanogaster
Q26365
312
34196
Y205
I
I
I
Y
R
A
A
Y
F
G
F
Y
D
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
Y272
I
I
V
Y
R
G
L
Y
F
G
L
Y
D
S
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
Y270
I
I
V
Y
R
G
L
Y
F
G
L
Y
D
S
V
Baker's Yeast
Sacchar. cerevisiae
P18238
307
33294
Y196
I
V
V
Y
R
G
L
Y
F
G
M
F
D
S
L
Red Bread Mold
Neurospora crassa
P02723
313
33870
Y198
I
V
V
Y
R
G
L
Y
F
G
L
Y
D
S
I
Conservation
Percent
Protein Identity:
100
53.5
N.A.
97.6
N.A.
98.6
98.9
N.A.
N.A.
92.9
22.2
92.6
92.2
77.5
N.A.
N.A.
N.A.
Protein Similarity:
100
56.7
N.A.
98.9
N.A.
99.3
99.6
N.A.
N.A.
95.9
36.7
96.9
96.3
83.9
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
N.A.
100
40
100
100
93.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
46.6
100
100
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
43.6
N.A.
43.9
54
50.1
Protein Similarity:
N.A.
53.7
N.A.
54
68
64.8
P-Site Identity:
N.A.
60
N.A.
60
46.6
53.3
P-Site Similarity:
N.A.
80
N.A.
80
80
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
65
65
0
0
8
0
0
0
0
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
93
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
36
0
0
0
93
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
86
65
0
0
0
8
0
0
0
58
0
0
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
29
0
8
0
22
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% T
% Val:
0
15
29
0
0
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
100
0
0
0
93
0
0
0
93
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _