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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CFI All Species: 5.15
Human Site: T165 Identified Species: 14.17
UniProt: P05156 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05156 NP_000195.2 583 65720 T165 G F Q Q G A D T Q R R F K L S
Chimpanzee Pan troglodytes XP_526653 583 65873 T165 G F Q Q G A D T Q R R F K L S
Rhesus Macaque Macaca mulatta XP_001087512 429 47612 C43 K K Y T H L S C N K V F C Q P
Dog Lupus familis XP_535694 599 67080 F181 L G F Q Q G A F D I Q K T F E
Cat Felis silvestris
Mouse Mus musculus Q61129 603 67216 Q170 P L G V R D I Q G S F N I S G
Rat Rattus norvegicus Q9WUW3 604 67279 Q170 P L G V R D I Q G R F N I P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506319 581 65768 H155 G H A Q G A L H H R Y A N D S
Chicken Gallus gallus XP_426329 596 67196 L181 C R H L G F E L G A E Y Y H T
Frog Xenopus laevis NP_001079421 600 66907 S164 F P S G A D A S A S D K V V P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 55.2 69.2 N.A. 68.3 69.2 N.A. 55.4 51.6 52.5 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 61.9 79.6 N.A. 78.6 78.9 N.A. 71.6 67.1 64.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 0 6.6 N.A. 40 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 13.3 N.A. 0 6.6 N.A. 40 26.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 34 23 0 12 12 0 12 0 0 0 % A
% Cys: 12 0 0 0 0 0 0 12 0 0 0 0 12 0 0 % C
% Asp: 0 0 0 0 0 34 23 0 12 0 12 0 0 12 0 % D
% Glu: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 12 % E
% Phe: 12 23 12 0 0 12 0 12 0 0 23 34 0 12 0 % F
% Gly: 34 12 23 12 45 12 0 0 34 0 0 0 0 0 12 % G
% His: 0 12 12 0 12 0 0 12 12 0 0 0 0 12 0 % H
% Ile: 0 0 0 0 0 0 23 0 0 12 0 0 23 0 0 % I
% Lys: 12 12 0 0 0 0 0 0 0 12 0 23 23 0 0 % K
% Leu: 12 23 0 12 0 12 12 12 0 0 0 0 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 23 12 0 0 % N
% Pro: 23 12 0 0 0 0 0 0 0 0 0 0 0 12 23 % P
% Gln: 0 0 23 45 12 0 0 23 23 0 12 0 0 12 0 % Q
% Arg: 0 12 0 0 23 0 0 0 0 45 23 0 0 0 0 % R
% Ser: 0 0 12 0 0 0 12 12 0 23 0 0 0 12 34 % S
% Thr: 0 0 0 12 0 0 0 23 0 0 0 0 12 0 12 % T
% Val: 0 0 0 23 0 0 0 0 0 0 12 0 12 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 12 12 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _