KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISG15
All Species:
13.94
Human Site:
S22
Identified Species:
34.07
UniProt:
P05161
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05161
NP_005092.1
165
17888
S22
F
Q
V
S
L
S
S
S
M
S
V
S
E
L
K
Chimpanzee
Pan troglodytes
XP_520842
165
17824
S22
F
Q
V
S
L
S
N
S
M
S
V
S
E
L
K
Rhesus Macaque
Macaca mulatta
XP_001088541
165
17996
S22
F
Q
V
S
L
S
N
S
M
S
V
S
E
L
K
Dog
Lupus familis
XP_536714
174
18986
S28
F
L
V
P
L
R
D
S
M
L
A
S
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64339
161
17879
T20
N
D
F
L
V
S
V
T
N
S
M
T
V
S
E
Rat
Rattus norvegicus
Q05474
74
7723
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687341
157
17670
V17
G
D
V
K
R
L
E
V
S
G
D
A
T
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P14792
76
8520
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59263
76
8506
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P13117
76
8579
Conservation
Percent
Protein Identity:
100
98.1
90.9
66
N.A.
63
20.6
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
100
99.3
95.1
70.6
N.A.
75.7
30.2
N.A.
N.A.
N.A.
N.A.
52.7
N.A.
N.A.
N.A.
30.2
N.A.
P-Site Identity:
100
93.3
93.3
60
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
60
N.A.
46.6
0
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
29.7
N.A.
31.5
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
40
0
10
% E
% Phe:
40
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
40
% K
% Leu:
0
10
0
10
40
10
0
0
0
10
0
0
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
40
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
30
0
40
10
40
10
40
0
40
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% T
% Val:
0
0
50
0
10
0
10
10
0
0
30
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _