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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPO All Species: 9.39
Human Site: T239 Identified Species: 18.79
UniProt: P05164 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05164 NP_000241.1 745 83869 T239 N E I V R F P T D Q L T P D Q
Chimpanzee Pan troglodytes XP_001162602 794 88781 T288 N E I V R F P T D Q L T P D Q
Rhesus Macaque Macaca mulatta XP_001103896 719 81232 P241 D H D L D F T P E P A A R A S
Dog Lupus familis XP_852445 734 82942 D234 P T E Q L T P D Q E R S L L F
Cat Felis silvestris
Mouse Mus musculus P11247 718 81052 D234 M Q W G Q F L D H D I T L T P
Rat Rattus norvegicus P14650 914 101442 H233 V W G Q Y I D H D I A L T P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506188 452 51695 I19 I S N Q N D C I P F F R S S P
Chicken Gallus gallus XP_415716 753 85100 P238 N E I V R F P P G Q L K F D Q
Frog Xenopus laevis NP_001081848 713 80479 T246 P E T P A R S T F L E G I D C
Zebra Danio Brachydanio rerio NP_997944 762 85101 T235 Q W V D H D L T F T P F S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 T841 V S T S L V A T K E I T P D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 T698 V S R Q L V A T E N I T P H S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.8 93 86.3 N.A. 82.9 36.8 N.A. 43.7 58.5 56.5 46.9 N.A. 23.2 N.A. 26.2 N.A.
Protein Similarity: 100 93 94 91 N.A. 88.7 50.4 N.A. 52.3 71.4 71.6 62.8 N.A. 34.5 N.A. 37.6 N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 13.3 N.A. 0 73.3 20 6.6 N.A. 26.6 N.A. 20 N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 33.3 13.3 N.A. 0 73.3 20 13.3 N.A. 40 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 17 0 0 0 17 9 0 9 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % C
% Asp: 9 0 9 9 9 17 9 17 25 9 0 0 0 42 0 % D
% Glu: 0 34 9 0 0 0 0 0 17 17 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 42 0 0 17 9 9 9 9 0 9 % F
% Gly: 0 0 9 9 0 0 0 0 9 0 0 9 0 0 0 % G
% His: 0 9 0 0 9 0 0 9 9 0 0 0 0 9 0 % H
% Ile: 9 0 25 0 0 9 0 9 0 9 25 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % K
% Leu: 0 0 0 9 25 0 17 0 0 9 25 9 17 9 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 25 0 9 0 9 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 17 0 0 9 0 0 34 17 9 9 9 0 34 17 17 % P
% Gln: 9 9 0 34 9 0 0 0 9 25 0 0 0 0 34 % Q
% Arg: 0 0 9 0 25 9 0 0 0 0 9 9 9 0 0 % R
% Ser: 0 25 0 9 0 0 9 0 0 0 0 9 17 9 25 % S
% Thr: 0 9 17 0 0 9 9 50 0 9 0 42 9 9 0 % T
% Val: 25 0 9 25 0 17 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _