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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCCA All Species: 39.09
Human Site: S634 Identified Species: 71.67
UniProt: P05165 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05165 NP_000273.2 703 77354 S634 E K V T E D T S S V L R S P M
Chimpanzee Pan troglodytes XP_001149000 728 80070 S659 E K V T E D T S S V L R S P M
Rhesus Macaque Macaca mulatta XP_001092670 728 79940 S659 E K V T E D T S S V L R S P M
Dog Lupus familis XP_534175 731 80859 S662 E K M A E D T S S I L R S P M
Cat Felis silvestris
Mouse Mus musculus Q91ZA3 724 79903 S655 E K V P K D T S S T L C S P M
Rat Rattus norvegicus P14882 704 77693 S635 E K V P K D T S S V L R S P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416970 713 78537 S644 E K A A E D T S S I L R S P M
Frog Xenopus laevis NP_001089298 710 78429 S641 E K V E E D T S S I L R S P M
Zebra Danio Brachydanio rerio NP_001002746 709 77797 S640 E K V P E D T S S I L R S P M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 S655 E K A K V D L S T V V L S P M
Sea Urchin Strong. purpuratus XP_787409 659 72714 S590 E K V K P D L S K E V V S P M
Poplar Tree Populus trichocarpa B9HBA8 528 57689 D472 R M K R A L D D T I I T G V P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 E648 G I E F S E D E E G V Q H R T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 94.2 88.5 N.A. 88.2 89.3 N.A. N.A. 81.7 77.7 76 N.A. N.A. N.A. 58 58.4
Protein Similarity: 100 96.4 95.4 93.5 N.A. 92.5 94.3 N.A. N.A. 88.3 86.9 86.7 N.A. N.A. N.A. 74 72.8
P-Site Identity: 100 100 100 80 N.A. 73.3 80 N.A. N.A. 80 86.6 86.6 N.A. N.A. N.A. 53.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 80 86.6 N.A. N.A. 86.6 93.3 93.3 N.A. N.A. N.A. 66.6 60
Percent
Protein Identity: 35.9 N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: 50.9 N.A. N.A. 59.1 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 16 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 85 16 8 0 0 0 0 0 0 0 % D
% Glu: 85 0 8 8 54 8 0 8 8 8 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 39 8 0 0 0 0 % I
% Lys: 0 85 8 16 16 0 0 0 8 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 8 16 0 0 0 70 8 0 0 0 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 77 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 24 8 0 0 0 0 0 0 0 0 85 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 0 0 8 0 0 0 0 0 0 0 62 0 8 0 % R
% Ser: 0 0 0 0 8 0 0 85 70 0 0 0 85 0 0 % S
% Thr: 0 0 0 24 0 0 70 0 16 8 0 8 0 0 8 % T
% Val: 0 0 62 0 8 0 0 0 0 39 24 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _