KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCCA
All Species:
11.82
Human Site:
T681
Identified Species:
21.67
UniProt:
P05165
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.58
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05165
NP_000273.2
703
77354
T681
M
T
A
G
K
T
G
T
V
K
S
V
H
C
Q
Chimpanzee
Pan troglodytes
XP_001149000
728
80070
T706
M
T
A
G
K
T
G
T
V
K
S
V
H
C
Q
Rhesus Macaque
Macaca mulatta
XP_001092670
728
79940
T706
M
T
A
G
K
T
G
T
V
K
S
V
H
C
Q
Dog
Lupus familis
XP_534175
731
80859
K709
M
T
A
G
K
T
G
K
V
K
S
V
H
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZA3
724
79903
K702
M
T
A
G
K
M
G
K
V
K
L
V
H
C
K
Rat
Rattus norvegicus
P14882
704
77693
K682
M
T
A
G
K
M
G
K
V
K
L
V
H
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416970
713
78537
K691
M
I
A
A
K
T
G
K
V
K
A
V
H
C
K
Frog
Xenopus laevis
NP_001089298
710
78429
K688
M
T
A
A
K
T
A
K
V
K
S
L
H
V
K
Zebra Danio
Brachydanio rerio
NP_001002746
709
77797
K687
M
T
A
A
K
T
A
K
V
K
S
V
H
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19842
724
79744
R702
L
H
A
G
K
T
G
R
V
K
A
V
N
V
K
Sea Urchin
Strong. purpuratus
XP_787409
659
72714
K637
L
F
S
S
R
D
G
K
V
K
A
V
H
F
V
Poplar Tree
Populus trichocarpa
B9HBA8
528
57689
E510
F
I
P
K
H
E
K
E
L
A
A
P
Q
Q
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
S711
V
K
A
P
S
S
G
S
I
Q
D
L
K
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
94.2
88.5
N.A.
88.2
89.3
N.A.
N.A.
81.7
77.7
76
N.A.
N.A.
N.A.
58
58.4
Protein Similarity:
100
96.4
95.4
93.5
N.A.
92.5
94.3
N.A.
N.A.
88.3
86.9
86.7
N.A.
N.A.
N.A.
74
72.8
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
N.A.
66.6
60
73.3
N.A.
N.A.
N.A.
53.3
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
80
73.3
80
N.A.
N.A.
N.A.
80
60
Percent
Protein Identity:
35.9
N.A.
N.A.
39.2
N.A.
N.A.
Protein Similarity:
50.9
N.A.
N.A.
59.1
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
85
24
0
0
16
0
0
8
31
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
54
0
0
77
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
77
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
8
0
8
77
0
8
54
0
85
0
0
8
0
62
% K
% Leu:
16
0
0
0
0
0
0
0
8
0
16
16
0
0
0
% L
% Met:
70
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
24
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
8
0
8
0
0
47
0
0
0
0
% S
% Thr:
0
62
0
0
0
62
0
24
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
85
0
0
77
0
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _