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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCCA All Species: 15.45
Human Site: T8 Identified Species: 28.33
UniProt: P05165 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05165 NP_000273.2 703 77354 T8 M L S A A L R T L K H V L Y Y
Chimpanzee Pan troglodytes XP_001149000 728 80070 T33 M L S A A L R T L K H V P Y Y
Rhesus Macaque Macaca mulatta XP_001092670 728 79940 T33 M L S A A L R T L K H V P H Y
Dog Lupus familis XP_534175 731 80859 T33 M R S A A L W T L K Y V P H Y
Cat Felis silvestris
Mouse Mus musculus Q91ZA3 724 79903 T29 S Q Q Q L L G T L K H A P V Y
Rat Rattus norvegicus P14882 704 77693 T9 S S Q Q L L W T L K R A P V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416970 713 78537 L18 A R G G R R A L R E C E T L C
Frog Xenopus laevis NP_001089298 710 78429 L15 A D V Q K L V L T W Q Q S T I
Zebra Danio Brachydanio rerio NP_001002746 709 77797 L14 A A G F Q R V L H A V K H V C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 A19 A N R G L A T A A V A R P G V
Sea Urchin Strong. purpuratus XP_787409 659 72714 R8 N R G E I P C R V M R T C R D
Poplar Tree Populus trichocarpa B9HBA8 528 57689
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 A8 M S M M T V W A L R R N V R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 94.2 88.5 N.A. 88.2 89.3 N.A. N.A. 81.7 77.7 76 N.A. N.A. N.A. 58 58.4
Protein Similarity: 100 96.4 95.4 93.5 N.A. 92.5 94.3 N.A. N.A. 88.3 86.9 86.7 N.A. N.A. N.A. 74 72.8
P-Site Identity: 100 93.3 86.6 66.6 N.A. 40 33.3 N.A. N.A. 0 6.6 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 93.3 93.3 80 N.A. 40 33.3 N.A. N.A. 6.6 6.6 0 N.A. N.A. N.A. 0 6.6
Percent
Protein Identity: 35.9 N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: 50.9 N.A. N.A. 59.1 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 8 0 31 31 8 8 16 8 8 8 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 16 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 0 0 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 24 16 0 0 8 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 31 0 8 16 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 0 0 0 0 47 0 8 0 0 0 % K
% Leu: 0 24 0 0 24 54 0 24 54 0 0 0 8 8 0 % L
% Met: 39 0 8 8 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 47 0 0 % P
% Gln: 0 8 16 24 8 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 24 8 0 8 16 24 8 8 8 24 8 0 16 8 % R
% Ser: 16 16 31 0 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 0 0 0 0 8 0 8 47 8 0 0 8 8 8 0 % T
% Val: 0 0 8 0 0 8 16 0 8 8 8 31 8 24 8 % V
% Trp: 0 0 0 0 0 0 24 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 16 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _