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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCCA All Species: 22.73
Human Site: Y31 Identified Species: 41.67
UniProt: P05165 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05165 NP_000273.2 703 77354 Y31 R N L G S V G Y D P N E K T F
Chimpanzee Pan troglodytes XP_001149000 728 80070 Y56 R N L G S V G Y D P N E K T F
Rhesus Macaque Macaca mulatta XP_001092670 728 79940 Y56 R N L G S V G Y D P N E K T F
Dog Lupus familis XP_534175 731 80859 Y56 R S F C S A G Y D S N E K T F
Cat Felis silvestris
Mouse Mus musculus Q91ZA3 724 79903 Y52 R S L S S V E Y E P K E K T F
Rat Rattus norvegicus P14882 704 77693 Y32 R S L S S V E Y E P K E K T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416970 713 78537 Y41 H K L Y S A V Y D P N E K T F
Frog Xenopus laevis NP_001089298 710 78429 H38 F V Q Y S T A H D P N E K T F
Zebra Danio Brachydanio rerio NP_001002746 709 77797 I37 I C R Y S T V I E P N D K T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19842 724 79744 I42 E I Y T T V G I D Y N E P K F
Sea Urchin Strong. purpuratus XP_787409 659 72714 A31 Y S E A D V N A L H V E M A D
Poplar Tree Populus trichocarpa B9HBA8 528 57689
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 M31 Y I S G S A S M K P K E Q C I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 94.2 88.5 N.A. 88.2 89.3 N.A. N.A. 81.7 77.7 76 N.A. N.A. N.A. 58 58.4
Protein Similarity: 100 96.4 95.4 93.5 N.A. 92.5 94.3 N.A. N.A. 88.3 86.9 86.7 N.A. N.A. N.A. 74 72.8
P-Site Identity: 100 100 100 66.6 N.A. 66.6 66.6 N.A. N.A. 66.6 53.3 40 N.A. N.A. N.A. 40 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 80 80 N.A. N.A. 66.6 60 53.3 N.A. N.A. N.A. 46.6 20
Percent
Protein Identity: 35.9 N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: 50.9 N.A. N.A. 59.1 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 24 8 8 0 0 0 0 0 8 0 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 8 0 0 0 54 0 0 8 0 0 8 % D
% Glu: 8 0 8 0 0 0 16 0 24 0 0 85 0 0 0 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 77 % F
% Gly: 0 0 0 31 0 0 39 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 8 16 0 0 0 0 0 16 0 0 0 0 0 0 8 % I
% Lys: 0 8 0 0 0 0 0 0 8 0 24 0 70 8 0 % K
% Leu: 0 0 47 0 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % M
% Asn: 0 24 0 0 0 0 8 0 0 0 62 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 8 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 47 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 31 8 16 77 0 8 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 8 8 16 0 0 0 0 0 0 0 70 0 % T
% Val: 0 8 0 0 0 54 16 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 8 24 0 0 0 54 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _