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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCCB
All Species:
40.61
Human Site:
S254
Identified Species:
74.44
UniProt:
P05166
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05166
NP_000523.2
539
58216
S254
A
K
T
H
T
T
M
S
G
V
A
H
R
A
F
Chimpanzee
Pan troglodytes
XP_001150022
595
64057
I281
Q
D
T
S
Y
L
F
I
T
G
P
D
V
V
K
Rhesus Macaque
Macaca mulatta
XP_001114982
539
58170
S254
A
K
T
H
T
T
M
S
G
V
A
H
R
A
F
Dog
Lupus familis
XP_534271
554
59958
S269
A
R
T
H
T
T
M
S
G
V
A
H
R
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99MN9
541
58375
S256
A
K
T
H
T
T
V
S
G
V
A
H
R
A
F
Rat
Rattus norvegicus
P07633
541
58608
S256
A
K
T
H
T
T
V
S
G
V
A
H
R
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231794
713
76377
S430
A
K
T
H
T
A
L
S
G
V
A
H
R
A
F
Frog
Xenopus laevis
NP_001083656
541
59015
S256
A
K
T
H
T
A
L
S
G
V
A
H
R
A
F
Zebra Danio
Brachydanio rerio
NP_998090
557
60772
S270
A
K
T
H
T
A
V
S
G
V
A
H
R
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9A7
578
62630
S269
A
D
L
H
C
K
T
S
G
V
T
D
H
Y
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34385
608
66505
S315
A
D
L
H
C
G
E
S
G
V
T
D
Y
Y
A
Sea Urchin
Strong. purpuratus
XP_796906
543
59143
S258
A
K
T
H
T
T
I
S
G
V
A
H
G
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDD8
587
63994
S288
A
T
V
H
C
T
V
S
G
V
S
D
Y
F
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
99
92.4
N.A.
92.2
91.3
N.A.
N.A.
65.3
83.5
80.6
N.A.
34
N.A.
26.9
75.8
Protein Similarity:
100
90.4
99.4
94.7
N.A.
96.4
96.1
N.A.
N.A.
71.2
91.3
87.6
N.A.
49.1
N.A.
43.4
84.9
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
86.6
N.A.
33.3
N.A.
33.3
86.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
33.3
N.A.
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
0
0
0
0
24
0
0
0
0
70
0
0
70
24
% A
% Cys:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
0
0
0
0
0
0
0
31
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
70
% F
% Gly:
0
0
0
0
0
8
0
0
93
8
0
0
8
0
0
% G
% His:
0
0
0
93
0
0
0
0
0
0
0
70
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
62
0
0
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
16
0
0
8
16
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
62
0
0
% R
% Ser:
0
0
0
8
0
0
0
93
0
0
8
0
0
0
0
% S
% Thr:
0
8
77
0
70
54
8
0
8
0
16
0
0
0
0
% T
% Val:
0
0
8
0
0
0
31
0
0
93
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
16
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _