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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCCB
All Species:
11.21
Human Site:
T45
Identified Species:
20.56
UniProt:
P05166
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05166
NP_000523.2
539
58216
T45
R
I
E
N
K
R
R
T
A
L
L
G
G
G
Q
Chimpanzee
Pan troglodytes
XP_001150022
595
64057
T72
R
I
E
N
K
R
R
T
A
L
L
G
G
G
Q
Rhesus Macaque
Macaca mulatta
XP_001114982
539
58170
T45
R
I
E
N
K
R
R
T
A
L
L
G
G
G
Q
Dog
Lupus familis
XP_534271
554
59958
A60
R
I
E
N
K
R
S
A
A
L
V
G
G
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99MN9
541
58375
A47
R
I
D
N
K
R
H
A
A
L
L
G
G
G
Q
Rat
Rattus norvegicus
P07633
541
58608
A47
R
I
E
N
K
R
H
A
A
L
L
G
G
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231794
713
76377
A221
R
I
E
E
K
R
R
A
A
L
L
G
G
G
Q
Frog
Xenopus laevis
NP_001083656
541
59015
E47
R
I
E
K
K
R
R
E
A
L
L
G
G
G
E
Zebra Danio
Brachydanio rerio
NP_998090
557
60772
A61
R
I
E
Q
K
R
Q
A
A
L
T
G
G
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9A7
578
62630
S50
E
N
A
R
E
M
A
S
L
V
G
D
L
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34385
608
66505
S69
H
H
C
S
A
D
K
S
T
L
Q
W
A
P
I
Sea Urchin
Strong. purpuratus
XP_796906
543
59143
Q49
R
I
D
E
K
R
Q
Q
A
L
L
G
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDD8
587
63994
V82
L
R
S
H
I
K
K
V
L
A
G
G
G
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
99
92.4
N.A.
92.2
91.3
N.A.
N.A.
65.3
83.5
80.6
N.A.
34
N.A.
26.9
75.8
Protein Similarity:
100
90.4
99.4
94.7
N.A.
96.4
96.1
N.A.
N.A.
71.2
91.3
87.6
N.A.
49.1
N.A.
43.4
84.9
P-Site Identity:
100
100
100
80
N.A.
80
86.6
N.A.
N.A.
86.6
80
73.3
N.A.
0
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
86.6
80
N.A.
20
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
39
77
8
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
62
16
8
0
0
8
0
0
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
16
85
85
77
0
% G
% His:
8
8
0
8
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
77
0
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
77
8
16
0
0
0
0
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
16
85
62
0
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
47
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
16
8
0
0
8
0
0
0
62
% Q
% Arg:
77
8
0
8
0
77
39
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
8
8
0
0
8
16
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
24
8
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _