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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCCB
All Species:
39.39
Human Site:
Y314
Identified Species:
72.22
UniProt:
P05166
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05166
NP_000523.2
539
58216
Y314
P
L
E
S
T
K
A
Y
N
M
V
D
I
I
H
Chimpanzee
Pan troglodytes
XP_001150022
595
64057
Y370
P
L
E
S
T
K
A
Y
N
M
V
D
I
I
H
Rhesus Macaque
Macaca mulatta
XP_001114982
539
58170
Y314
P
L
E
S
T
K
A
Y
N
M
V
D
I
I
H
Dog
Lupus familis
XP_534271
554
59958
Y329
P
L
E
S
T
K
A
Y
N
M
V
D
I
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99MN9
541
58375
Y316
P
L
E
S
S
K
A
Y
N
M
L
D
I
I
H
Rat
Rattus norvegicus
P07633
541
58608
Y316
P
L
E
S
S
K
A
Y
N
M
L
D
I
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231794
713
76377
Y490
P
V
E
S
T
K
A
Y
D
M
L
D
I
I
H
Frog
Xenopus laevis
NP_001083656
541
59015
Y316
P
M
E
S
T
K
A
Y
D
M
L
D
I
I
H
Zebra Danio
Brachydanio rerio
NP_998090
557
60772
Y330
P
F
E
S
T
K
A
Y
D
M
L
D
I
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9A7
578
62630
L332
P
R
Y
D
A
E
E
L
Y
G
I
V
G
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34385
608
66505
N369
I
Y
G
I
V
G
S
N
L
K
K
T
Y
D
V
Sea Urchin
Strong. purpuratus
XP_796906
543
59143
Y318
P
L
E
S
N
K
P
Y
S
M
K
D
V
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDD8
587
63994
D348
L
R
S
I
A
P
V
D
H
K
Q
Q
F
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
99
92.4
N.A.
92.2
91.3
N.A.
N.A.
65.3
83.5
80.6
N.A.
34
N.A.
26.9
75.8
Protein Similarity:
100
90.4
99.4
94.7
N.A.
96.4
96.1
N.A.
N.A.
71.2
91.3
87.6
N.A.
49.1
N.A.
43.4
84.9
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
80
80
73.3
N.A.
6.6
N.A.
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
26.6
N.A.
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
70
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
24
0
0
77
0
16
0
% D
% Glu:
0
0
77
0
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
8
0
0
8
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
70
% H
% Ile:
8
0
0
16
0
0
0
0
0
0
8
0
70
70
0
% I
% Lys:
0
0
0
0
0
77
0
0
0
16
16
0
0
0
0
% K
% Leu:
8
54
0
0
0
0
0
8
8
0
39
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
77
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
47
0
0
0
0
0
8
% N
% Pro:
85
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
77
16
0
8
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
54
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
8
0
0
8
0
8
0
0
0
31
8
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
77
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _