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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
32.73
Human Site:
S432
Identified Species:
60
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
S432
G
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
N862
S
G
V
R
P
D
V
N
E
S
E
S
G
D
P
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
S560
G
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Dog
Lupus familis
XP_535374
522
57256
S429
G
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
S432
D
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Rat
Rattus norvegicus
P08289
524
57641
S432
D
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
K421
Y
G
N
G
P
G
Y
K
I
V
G
G
E
R
E
Frog
Xenopus laevis
NP_001080895
526
57659
S432
N
G
Q
R
E
N
V
S
T
V
D
F
S
H
P
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
S438
N
G
T
R
G
N
V
S
V
L
D
Y
Y
D
E
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
S435
N
G
G
R
E
N
V
S
A
I
D
Y
Q
E
N
Fruit Fly
Dros. melanogaster
Q24238
596
65244
T482
W
M
P
L
K
H
F
T
A
E
E
R
A
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
S432
D
G
E
R
E
N
V
S
M
V
D
Y
A
H
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
A462
H
L
D
D
N
A
N
A
I
Q
D
K
L
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
60
46.6
60
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
93.3
93.3
N.A.
N.A.
20
80
60
66.6
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
16
0
0
0
54
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
8
8
0
8
0
0
0
0
77
0
0
16
8
% D
% Glu:
0
0
47
0
62
0
0
0
8
8
16
0
8
8
16
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
24
85
8
8
8
8
0
0
0
0
8
8
8
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
54
0
% H
% Ile:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
8
0
0
0
0
0
8
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
47
0
0
0
0
0
0
% M
% Asn:
24
0
8
0
8
70
8
8
0
0
0
0
0
8
54
% N
% Pro:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
24
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
0
77
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
8
0
0
0
0
0
0
70
0
8
0
8
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
77
0
8
62
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
62
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _