KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
29.7
Human Site:
T373
Identified Species:
54.44
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
T373
T
S
S
E
D
T
L
T
V
V
T
A
D
H
S
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
L803
L
T
S
E
E
D
T
L
T
L
V
T
A
D
H
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
T501
T
S
L
E
D
T
L
T
V
V
T
A
D
H
S
Dog
Lupus familis
XP_535374
522
57256
T370
T
S
L
E
D
T
L
T
V
V
T
A
D
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
T373
T
S
Q
K
D
T
L
T
V
V
T
A
D
H
S
Rat
Rattus norvegicus
P08289
524
57641
T373
T
S
Q
K
D
T
L
T
V
V
T
A
D
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
G362
D
R
A
V
G
L
A
G
R
L
T
S
P
R
D
Frog
Xenopus laevis
NP_001080895
526
57659
T373
T
S
V
E
D
T
L
T
V
V
T
A
D
H
S
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
L379
L
T
S
E
S
D
T
L
T
V
V
T
A
D
H
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
T376
T
S
I
H
D
T
L
T
I
V
T
A
D
H
S
Fruit Fly
Dros. melanogaster
Q24238
596
65244
N423
H
S
H
A
V
T
F
N
G
Y
A
L
R
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
T373
T
S
Q
K
D
T
L
T
V
V
T
A
D
H
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
T403
P
Q
V
L
A
N
A
T
H
S
G
E
F
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
93.3
20
80
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
93.3
26.6
86.6
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
16
0
0
0
8
62
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
62
16
0
0
0
0
0
0
62
16
8
% D
% Glu:
0
0
0
47
8
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
8
0
8
0
0
8
0
% G
% His:
8
0
8
8
0
0
0
0
8
0
0
0
0
62
16
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
16
0
16
8
0
8
62
16
0
16
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
24
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
0
8
8
0
% R
% Ser:
0
70
24
0
8
0
0
0
0
8
0
8
0
0
62
% S
% Thr:
62
16
0
0
0
70
16
70
16
0
70
16
0
0
0
% T
% Val:
0
0
16
8
8
0
0
0
54
70
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _