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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
39.39
Human Site:
Y297
Identified Species:
72.22
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
Y297
F
E
P
G
D
M
Q
Y
E
L
N
R
N
N
V
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
Y728
F
E
P
G
D
T
K
Y
E
I
H
R
D
P
T
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
Y425
F
E
P
G
D
M
E
Y
E
L
N
R
N
N
V
Dog
Lupus familis
XP_535374
522
57256
Y294
F
E
P
G
D
M
Q
Y
E
L
N
R
N
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
Y297
F
E
P
G
D
M
Q
Y
E
L
N
R
N
N
L
Rat
Rattus norvegicus
P08289
524
57641
Y297
F
E
P
G
D
M
Q
Y
E
L
N
R
N
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
Y296
F
E
P
G
D
M
V
Y
E
L
D
R
N
N
E
Frog
Xenopus laevis
NP_001080895
526
57659
Y297
F
E
P
V
D
M
L
Y
D
L
E
R
N
T
T
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
F304
F
E
P
K
D
M
R
F
E
V
F
R
N
R
T
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
Y300
F
E
P
E
D
M
T
Y
D
L
E
R
N
P
E
Fruit Fly
Dros. melanogaster
Q24238
596
65244
Y333
F
R
N
N
H
I
T
Y
S
I
A
R
E
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
Y297
F
E
P
G
D
M
Q
Y
E
L
N
R
N
N
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
S311
L
G
A
L
E
K
A
S
N
E
D
K
D
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
80
60
53.3
60
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
86.6
66.6
73.3
66.6
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
85
0
0
0
16
0
16
0
16
0
0
% D
% Glu:
0
85
0
8
8
0
8
0
70
8
16
0
8
0
16
% E
% Phe:
93
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
62
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
8
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
8
0
0
8
0
0
70
0
0
0
0
24
% L
% Met:
0
0
0
0
0
77
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
8
0
47
0
77
54
8
% N
% Pro:
0
0
85
0
0
0
0
0
0
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
93
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
16
0
0
0
0
0
0
8
24
% T
% Val:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _