KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPP
All Species:
20.91
Human Site:
Y441
Identified Species:
38.33
UniProt:
P05187
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05187
NP_001623.3
535
57954
Y441
S
E
S
G
S
P
E
Y
R
Q
Q
S
A
V
P
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
Y440
S
E
S
G
S
P
E
Y
R
Q
Q
S
A
V
P
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
N568
M
V
D
Y
A
H
N
N
Y
Q
A
Q
S
A
V
Dog
Lupus familis
XP_534605
554
59751
Y441
A
E
S
R
D
P
A
Y
K
P
Q
A
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
Y437
E
E
S
S
N
P
T
Y
Q
Q
Q
A
C
V
P
Rat
Rattus norvegicus
P15693
540
58384
Y439
A
E
S
G
D
V
N
Y
K
Q
Q
A
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
D434
R
E
N
V
S
A
V
D
F
A
H
A
N
Y
Q
Frog
Xenopus laevis
NP_001091135
530
58155
Y440
N
L
S
E
D
V
N
Y
M
Q
Q
A
A
V
P
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
Y438
S
V
S
G
R
D
D
Y
L
Q
Q
A
A
V
P
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
N443
A
I
D
Y
Q
E
N
N
Y
Q
A
Q
A
A
V
Fruit Fly
Dros. melanogaster
Q24238
596
65244
P477
N
S
S
N
M
W
M
P
L
K
H
F
T
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
N440
M
V
D
Y
A
H
N
N
Y
Q
A
Q
S
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
H433
K
I
E
N
F
I
K
H
E
I
L
E
K
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
46.4
71.1
N.A.
73.8
72.4
N.A.
N.A.
55.5
60
55.7
53.4
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
96
58.9
79.2
N.A.
83.3
82.5
N.A.
N.A.
69.9
74
71
68.6
54.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
53.3
N.A.
53.3
60
N.A.
N.A.
13.3
46.6
60
13.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
73.3
N.A.
73.3
80
N.A.
N.A.
26.6
60
73.3
20
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.2
N.A.
N.A.
25
N.A.
Protein Similarity:
N.A.
71.7
N.A.
N.A.
42.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
16
8
8
0
0
8
24
47
54
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
24
0
24
8
8
8
0
0
0
0
0
8
0
% D
% Glu:
8
47
8
8
0
8
16
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
16
0
8
0
0
16
0
0
0
0
% H
% Ile:
0
16
0
0
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
16
8
0
0
8
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
16
0
8
0
0
0
8
% L
% Met:
16
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
16
0
8
16
8
0
39
24
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
31
0
8
0
8
0
0
0
0
54
% P
% Gln:
0
0
0
0
8
0
0
0
8
70
54
24
0
0
8
% Q
% Arg:
8
0
0
8
8
0
0
0
16
0
0
0
0
0
0
% R
% Ser:
24
8
62
8
24
0
0
0
0
0
0
16
16
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% T
% Val:
0
24
0
8
0
16
8
0
0
0
0
0
0
54
24
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
0
0
54
24
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _