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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICAM1
All Species:
13.33
Human Site:
S275
Identified Species:
48.89
UniProt:
P05362
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05362
NP_000192.2
532
57825
S275
D
S
F
S
A
K
A
S
V
S
V
T
A
E
D
Chimpanzee
Pan troglodytes
Q28806
532
57739
S275
D
S
F
S
A
K
A
S
V
S
V
T
A
E
D
Rhesus Macaque
Macaca mulatta
Q5NKV6
532
57621
S275
N
S
L
S
A
K
A
S
V
K
V
T
A
E
E
Dog
Lupus familis
XP_542075
676
72790
N418
D
S
L
L
A
T
A
N
V
K
A
N
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P13597
537
58826
L277
D
S
V
S
A
T
A
L
V
E
V
T
E
E
F
Rat
Rattus norvegicus
Q00238
545
60123
S275
D
F
V
S
A
T
A
S
V
E
V
T
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517194
624
67678
T273
D
R
L
T
A
E
A
T
V
Q
A
E
E
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
87
49.4
N.A.
53.4
52.2
N.A.
27
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
93
60.6
N.A.
67.4
65.1
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
46.6
N.A.
60
53.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
53.3
N.A.
60
60
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
100
0
100
0
0
0
29
0
43
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
86
0
0
0
0
0
0
0
0
0
0
0
0
0
43
% D
% Glu:
0
0
0
0
0
15
0
0
0
29
0
15
43
72
15
% E
% Phe:
0
15
29
0
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
43
0
0
0
29
0
0
0
15
0
% K
% Leu:
0
0
43
15
0
0
0
15
0
0
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
15
0
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
72
0
72
0
0
0
58
0
29
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
43
0
15
0
0
0
72
0
0
0
% T
% Val:
0
0
29
0
0
0
0
0
100
0
72
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _