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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPLP0 All Species: 38.79
Human Site: S46 Identified Species: 53.33
UniProt: P05388 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05388 NP_000993.1 317 34274 S46 Q M Q Q I R M S L R G K A V V
Chimpanzee Pan troglodytes XP_001168269 317 34259 S46 Q M Q Q I H M S L R G K V V V
Rhesus Macaque Macaca mulatta XP_001115939 275 30225 K38 G A D N V G S K Q M Q Q I R M
Dog Lupus familis XP_535894 317 34269 S46 Q M Q Q I R M S L R G K A V V
Cat Felis silvestris
Mouse Mus musculus P14869 317 34198 S46 Q M Q Q I R M S L R G K A V V
Rat Rattus norvegicus P19945 317 34197 S46 Q M Q Q I R M S L R G K A V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515492 264 29009 C27 L L D D Y P K C F I V G A D N
Chicken Gallus gallus P47826 316 34267 S46 Q M Q Q I R M S L R G K A V V
Frog Xenopus laevis NP_001080134 315 34079 S46 Q M Q Q I R M S L R G K A V V
Zebra Danio Brachydanio rerio Q9PV90 319 34735 S46 Q M Q T I R L S L R G K A V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19889 317 34184 S46 Q M Q N I R T S L R G L A V V
Honey Bee Apis mellifera XP_623106 317 34396 S46 Q M Q Q I R M S L R G N A V V
Nematode Worm Caenorhab. elegans Q93572 312 33755 A46 Q M Q E I R Q A M R G H A E I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays O24573 319 34486 G47 Q L Q D I R R G L R G D S V V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04204 317 33648 G47 Q L Q N I R K G L R G D S V V
Baker's Yeast Sacchar. cerevisiae P05317 312 33748 R48 V R K E L R G R A V V L M G K
Red Bread Mold Neurospora crassa Q96TJ5 313 33516 N56 A V V L M G K N T M V R R A L
Conservation
Percent
Protein Identity: 100 96.8 86.4 99.6 N.A. 97.4 98.1 N.A. 80.4 95.2 91.4 87.4 N.A. 66.2 70.9 67.5 N.A.
Protein Similarity: 100 98.1 86.4 100 N.A. 98.4 99.3 N.A. 82.9 97.4 95.9 94.3 N.A. 80.4 82 81.3 N.A.
P-Site Identity: 100 86.6 0 100 N.A. 100 100 N.A. 6.6 100 100 86.6 N.A. 80 93.3 53.3 N.A.
P-Site Similarity: 100 86.6 20 100 N.A. 100 100 N.A. 13.3 100 100 93.3 N.A. 80 93.3 80 N.A.
Percent
Protein Identity: N.A. 52.9 N.A. 51.7 54.8 55.2
Protein Similarity: N.A. 69.5 N.A. 68.7 74.1 74.1
P-Site Identity: N.A. 60 N.A. 60 6.6 0
P-Site Similarity: N.A. 73.3 N.A. 73.3 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 0 0 0 0 6 6 0 0 0 65 6 0 % A
% Cys: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 12 0 0 0 0 0 0 0 12 0 6 0 % D
% Glu: 0 0 0 12 0 0 0 0 0 0 0 0 0 6 0 % E
% Phe: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % F
% Gly: 6 0 0 0 0 12 6 12 0 0 77 6 0 6 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 0 6 0 0 0 % H
% Ile: 0 0 0 0 77 0 0 0 0 6 0 0 6 0 6 % I
% Lys: 0 0 6 0 0 0 18 6 0 0 0 48 0 0 6 % K
% Leu: 6 18 0 6 6 0 6 0 71 0 0 12 0 0 6 % L
% Met: 0 65 0 0 6 0 48 0 6 12 0 0 6 0 6 % M
% Asn: 0 0 0 18 0 0 0 6 0 0 0 6 0 0 6 % N
% Pro: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % P
% Gln: 77 0 77 48 0 0 6 0 6 0 6 6 0 0 0 % Q
% Arg: 0 6 0 0 0 77 6 6 0 77 0 6 6 6 0 % R
% Ser: 0 0 0 0 0 0 6 59 0 0 0 0 12 0 0 % S
% Thr: 0 0 0 6 0 0 6 0 6 0 0 0 0 0 0 % T
% Val: 6 6 6 0 6 0 0 0 0 6 18 0 6 71 71 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _