Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPLP0 All Species: 43.03
Human Site: Y257 Identified Species: 59.17
UniProt: P05388 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05388 NP_000993.1 317 34274 Y257 A L S V E T D Y T F P L A E K
Chimpanzee Pan troglodytes XP_001168269 317 34259 Y257 A L S V E T D Y T F P L A E K
Rhesus Macaque Macaca mulatta XP_001115939 275 30225 N221 R F L E G V R N V A S V C L Q
Dog Lupus familis XP_535894 317 34269 Y257 A L S V E T D Y T F P L A E K
Cat Felis silvestris
Mouse Mus musculus P14869 317 34198 Y257 A L S V E T E Y T F P L T E K
Rat Rattus norvegicus P19945 317 34197 Y257 A L S V E T D Y T F P L A E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515492 264 29009 T210 V L D I T E D T L H T R F L E
Chicken Gallus gallus P47826 316 34267 Y257 A V A V E T D Y T F P L A E K
Frog Xenopus laevis NP_001080134 315 34079 Y257 A I A V E T D Y S F P L A D K
Zebra Danio Brachydanio rerio Q9PV90 319 34735 Y260 A V T V E T D Y T F P L A E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19889 317 34184 V257 A I A A T T E V E F K E A T T
Honey Bee Apis mellifera XP_623106 317 34396 I257 A I A A V T D I E F P E A T T
Nematode Worm Caenorhab. elegans Q93572 312 33755 V257 G V A A V T D V S F K E A E T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays O24573 319 34486 Y260 A V A V E T D Y S Y P H A D K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04204 317 33648 Y260 A V A L A T E Y S F P Q A E N
Baker's Yeast Sacchar. cerevisiae P05317 312 33748 Y255 A V A I A A S Y H Y P E I E D
Red Bread Mold Neurospora crassa Q96TJ5 313 33516 I255 A V A I E T E I S W P E I E E
Conservation
Percent
Protein Identity: 100 96.8 86.4 99.6 N.A. 97.4 98.1 N.A. 80.4 95.2 91.4 87.4 N.A. 66.2 70.9 67.5 N.A.
Protein Similarity: 100 98.1 86.4 100 N.A. 98.4 99.3 N.A. 82.9 97.4 95.9 94.3 N.A. 80.4 82 81.3 N.A.
P-Site Identity: 100 100 0 100 N.A. 86.6 100 N.A. 13.3 86.6 73.3 86.6 N.A. 26.6 40 33.3 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 100 N.A. 26.6 100 100 100 N.A. 46.6 53.3 53.3 N.A.
Percent
Protein Identity: N.A. 52.9 N.A. 51.7 54.8 55.2
Protein Similarity: N.A. 69.5 N.A. 68.7 74.1 74.1
P-Site Identity: N.A. 60 N.A. 46.6 26.6 33.3
P-Site Similarity: N.A. 93.3 N.A. 80 53.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 83 0 53 18 12 6 0 0 0 6 0 0 71 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % C
% Asp: 0 0 6 0 0 0 65 0 0 0 0 0 0 12 6 % D
% Glu: 0 0 0 6 59 6 24 0 12 0 0 30 0 65 12 % E
% Phe: 0 6 0 0 0 0 0 0 0 71 0 0 6 0 0 % F
% Gly: 6 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 6 0 6 0 0 0 % H
% Ile: 0 18 0 18 0 0 0 12 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 53 % K
% Leu: 0 36 6 6 0 0 0 0 6 0 0 48 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 77 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 6 % Q
% Arg: 6 0 0 0 0 0 6 0 0 0 0 6 0 0 0 % R
% Ser: 0 0 30 0 0 0 6 0 30 0 6 0 0 0 0 % S
% Thr: 0 0 6 0 12 83 0 6 42 0 6 0 6 12 18 % T
% Val: 6 42 0 53 12 6 0 12 6 0 0 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _