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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
20.61
Human Site:
S250
Identified Species:
45.33
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
S250
P
G
L
P
K
D
V
S
V
A
E
L
L
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
S249
P
G
L
P
K
D
V
S
V
A
E
L
L
R
E
Dog
Lupus familis
XP_851340
540
59514
S392
P
G
L
P
K
D
I
S
V
A
E
L
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
S250
P
G
L
P
K
D
V
S
V
A
E
L
L
R
E
Rat
Rattus norvegicus
NP_001026823
398
44352
S250
P
G
L
P
K
D
V
S
V
A
E
L
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
V204
G
L
P
R
D
V
S
V
S
E
L
L
K
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
S248
P
P
E
T
K
D
V
S
F
P
E
M
L
E
S
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
L236
P
P
M
P
K
A
D
L
L
P
D
L
L
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
Q237
L
A
V
A
Q
H
L
Q
Q
L
H
V
A
A
Q
Honey Bee
Apis mellifera
XP_624732
340
37456
I204
A
P
V
V
L
P
M
I
K
E
D
S
I
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
V255
D
D
F
D
T
G
R
V
T
C
A
T
I
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
6.6
N.A.
46.6
33.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
53.3
53.3
N.A.
33.3
33.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
10
0
0
0
46
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
10
0
10
10
55
10
0
0
0
19
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
19
55
0
0
28
46
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
10
46
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
0
19
0
0
% I
% Lys:
0
0
0
0
64
0
0
0
10
0
0
0
10
0
10
% K
% Leu:
10
10
46
0
10
0
10
10
10
10
10
64
64
0
10
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
64
28
10
55
0
10
0
0
0
19
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
0
10
0
0
0
0
0
0
46
0
% R
% Ser:
0
0
0
0
0
0
10
55
10
0
0
10
0
0
19
% S
% Thr:
0
0
0
10
10
0
0
0
10
0
0
10
0
0
0
% T
% Val:
0
0
19
10
0
10
46
19
46
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _