KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
31.82
Human Site:
S386
Identified Species:
70
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
S386
V
K
H
K
L
V
C
S
P
D
F
E
S
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
S385
V
K
H
K
L
V
C
S
P
D
F
E
S
L
L
Dog
Lupus familis
XP_851340
540
59514
S528
I
K
H
K
L
V
C
S
P
D
F
E
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
S386
V
K
H
K
L
V
C
S
P
D
F
E
S
L
L
Rat
Rattus norvegicus
NP_001026823
398
44352
S386
V
K
H
K
L
V
C
S
P
D
F
E
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
D162
S
G
N
A
K
E
E
D
M
E
V
D
V
P
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
S383
I
Q
H
K
L
V
C
S
P
D
F
E
S
L
L
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
S370
V
K
H
K
L
V
C
S
P
D
F
Q
A
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
A391
P
I
Q
A
K
L
K
A
T
P
D
W
V
H
L
Honey Bee
Apis mellifera
XP_624732
340
37456
C329
P
V
N
S
T
L
I
C
S
P
D
W
E
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
T388
I
K
H
R
V
I
C
T
P
D
F
E
S
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
0
N.A.
86.6
86.6
N.A.
6.6
0
N.A.
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
N.A.
100
100
N.A.
20
20
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
73
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
73
19
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
10
0
64
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
73
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
28
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
64
0
64
19
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
64
19
0
0
0
0
0
0
0
73
82
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
73
19
0
0
0
10
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
0
0
0
64
10
0
0
0
64
10
0
% S
% Thr:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
10
% T
% Val:
46
10
0
0
10
64
0
0
0
0
10
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _