KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
20.61
Human Site:
T126
Identified Species:
45.33
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
T126
K
K
G
N
W
D
K
T
V
D
V
S
D
M
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
T126
K
K
G
N
W
D
K
T
V
D
V
S
D
M
G
Dog
Lupus familis
XP_851340
540
59514
T268
K
K
G
N
W
D
K
T
V
D
V
S
D
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
T126
K
K
G
N
W
D
K
T
V
D
M
S
D
M
G
Rat
Rattus norvegicus
NP_001026823
398
44352
T126
K
K
G
N
W
D
K
T
V
D
M
S
D
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
T126
D
P
G
L
K
N
D
T
R
N
K
P
V
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
P120
K
K
I
G
W
D
G
P
A
E
S
T
D
F
G
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
A121
R
R
G
V
Y
D
D
A
R
E
T
A
N
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
T143
R
R
S
T
G
N
G
T
A
Y
A
R
G
G
E
Honey Bee
Apis mellifera
XP_624732
340
37456
L123
R
G
R
G
S
N
N
L
I
Q
S
S
G
I
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
D148
L
L
R
E
L
V
R
D
D
F
I
S
D
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
40
20
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
N.A.
53.3
60
N.A.
26.6
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
19
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
64
19
10
10
46
0
0
64
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
19
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
10
64
19
10
0
19
0
0
0
0
0
19
10
73
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
10
0
0
10
0
% I
% Lys:
55
55
0
0
10
0
46
0
0
0
10
0
0
0
0
% K
% Leu:
10
10
0
10
10
0
0
10
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
19
0
0
46
0
% M
% Asn:
0
0
0
46
0
28
10
0
0
10
0
0
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
28
19
19
0
0
0
10
0
19
0
0
10
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
0
0
0
19
64
0
10
0
% S
% Thr:
0
0
0
10
0
0
0
64
0
0
10
10
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
46
0
28
0
10
0
0
% V
% Trp:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _