KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
23.64
Human Site:
T147
Identified Species:
52
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
T147
I
K
K
E
K
R
E
T
D
E
E
T
K
Q
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
T147
I
K
K
E
K
R
E
T
D
E
E
T
K
Q
I
Dog
Lupus familis
XP_851340
540
59514
T289
I
K
K
E
K
R
E
T
D
E
E
T
K
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
T147
I
K
K
E
K
R
E
T
D
E
E
T
K
Q
I
Rat
Rattus norvegicus
NP_001026823
398
44352
T147
I
K
K
E
K
R
E
T
D
E
E
T
K
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
E147
W
L
F
K
E
E
S
E
E
P
D
A
Q
P
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
T141
I
K
R
E
K
R
E
T
E
E
E
T
K
E
I
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
E142
I
K
K
E
R
E
T
E
E
E
T
K
E
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
D164
K
R
V
D
R
K
D
D
K
S
Q
A
E
R
I
Honey Bee
Apis mellifera
XP_624732
340
37456
S144
T
A
G
K
R
Y
S
S
G
S
R
D
S
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
P169
R
Y
Q
P
I
S
L
P
M
A
K
P
F
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
80
33.3
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
40
N.A.
100
60
N.A.
60
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
10
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
10
46
0
10
10
0
10
0
% D
% Glu:
0
0
0
64
10
19
55
19
28
64
55
0
19
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
0
0
0
10
0
0
0
0
0
0
0
0
10
64
% I
% Lys:
10
64
55
19
55
10
0
0
10
0
10
10
55
10
0
% K
% Leu:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
10
0
10
0
10
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
10
0
10
46
0
% Q
% Arg:
10
10
10
0
28
55
0
0
0
0
10
0
0
10
10
% R
% Ser:
0
0
0
0
0
10
19
10
0
19
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
10
55
0
0
10
55
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _