KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
19.39
Human Site:
T242
Identified Species:
42.67
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
T242
P
P
K
A
A
R
K
T
P
G
L
P
K
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
T241
P
P
K
A
A
R
K
T
P
G
L
P
K
D
V
Dog
Lupus familis
XP_851340
540
59514
T384
P
P
R
T
A
R
K
T
P
G
L
P
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
T242
P
P
R
A
A
R
K
T
P
G
L
P
K
D
V
Rat
Rattus norvegicus
NP_001026823
398
44352
T242
P
P
R
A
A
R
K
T
P
G
L
P
K
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
P196
A
K
A
A
R
K
A
P
G
L
P
R
D
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
K240
A
K
A
P
I
I
K
K
P
P
E
T
K
D
V
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
L228
K
V
E
P
A
F
K
L
P
P
M
P
K
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
T229
S
T
S
T
L
K
D
T
L
A
V
A
Q
H
L
Honey Bee
Apis mellifera
XP_624732
340
37456
N196
G
E
S
I
N
L
S
N
A
P
V
V
L
P
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
Q247
V
S
I
S
D
A
F
Q
D
D
F
D
T
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
6.6
N.A.
33.3
33.3
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
13.3
N.A.
33.3
46.6
N.A.
33.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
46
55
10
10
0
10
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
10
10
0
10
10
55
10
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
10
46
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
10
10
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
19
19
0
0
19
64
10
0
0
0
0
64
0
0
% K
% Leu:
0
0
0
0
10
10
0
10
10
10
46
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
46
46
0
19
0
0
0
10
64
28
10
55
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Q
% Arg:
0
0
28
0
10
46
0
0
0
0
0
10
0
0
10
% R
% Ser:
10
10
19
10
0
0
10
0
0
0
0
0
0
0
10
% S
% Thr:
0
10
0
19
0
0
0
55
0
0
0
10
10
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
0
19
10
0
10
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _