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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
36.67
Human Site:
T274
Identified Species:
80.67
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
T274
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
T273
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Dog
Lupus familis
XP_851340
540
59514
T416
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
T274
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Rat
Rattus norvegicus
NP_001026823
398
44352
T274
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
T228
L
F
L
Q
L
P
D
T
L
P
G
Q
P
P
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
T272
F
F
M
Q
L
P
D
T
L
P
G
Q
P
P
S
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
S260
L
F
M
Q
L
P
D
S
L
P
G
Q
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
T261
Q
Y
G
R
Y
P
R
T
I
G
N
F
L
D
S
Honey Bee
Apis mellifera
XP_624732
340
37456
C228
I
L
M
Q
F
P
D
C
L
P
G
L
V
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
T279
L
F
F
Q
L
P
D
T
L
P
G
L
P
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
80
86.6
N.A.
13.3
40
N.A.
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
100
N.A.
40
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
91
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
82
10
0
10
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
91
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
73
10
55
0
82
0
0
0
91
0
0
19
10
0
0
% L
% Met:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
100
0
0
0
91
0
0
82
73
0
% P
% Gln:
10
0
0
91
0
0
0
0
0
0
0
73
0
0
0
% Q
% Arg:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
28
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
64
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _