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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3D
All Species:
22.12
Human Site:
T374
Identified Species:
48.67
UniProt:
P05423
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05423
NP_001713.2
398
44396
T374
D
S
R
T
G
E
M
T
V
L
G
H
V
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102894
397
44314
T373
D
S
R
T
G
E
M
T
V
L
G
H
V
K
H
Dog
Lupus familis
XP_851340
540
59514
T516
D
S
R
T
G
E
M
T
V
L
G
H
I
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD1
398
44304
T374
D
S
R
T
G
E
M
T
V
L
G
H
V
K
H
Rat
Rattus norvegicus
NP_001026823
398
44352
T374
D
S
R
T
G
E
M
T
V
L
G
H
V
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517356
385
42535
E328
R
W
W
V
G
S
G
E
X
X
X
X
S
G
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089656
395
43847
M371
E
S
R
G
G
E
M
M
V
L
G
H
I
Q
H
Zebra Danio
Brachydanio rerio
NP_956581
381
42246
S358
E
G
R
R
G
D
M
S
V
L
G
H
V
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649028
415
43950
M379
R
E
Q
R
S
G
N
M
I
N
L
G
P
I
Q
Honey Bee
Apis mellifera
XP_624732
340
37456
L317
T
E
N
L
N
G
D
L
I
N
L
G
P
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181403
399
43858
L376
G
E
E
M
S
E
M
L
T
L
G
H
I
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
69.6
N.A.
93.9
94.4
N.A.
70.8
N.A.
65.8
57
N.A.
22.4
22.1
N.A.
33.5
Protein Similarity:
100
N.A.
99.2
72.7
N.A.
98.2
98.7
N.A.
77.1
N.A.
80.4
71.3
N.A.
36.8
42.4
N.A.
49.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
6.6
N.A.
66.6
66.6
N.A.
0
0
N.A.
46.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
N.A.
86.6
86.6
N.A.
13.3
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
19
28
10
0
0
64
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
73
19
10
0
0
0
73
19
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
73
% H
% Ile:
0
0
0
0
0
0
0
0
19
0
0
0
28
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% K
% Leu:
0
0
0
10
0
0
0
19
0
73
19
0
0
0
0
% L
% Met:
0
0
0
10
0
0
73
19
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
10
0
0
19
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
19
0
64
19
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
55
0
0
19
10
0
10
0
0
0
0
10
0
0
% S
% Thr:
10
0
0
46
0
0
0
46
10
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
64
0
0
0
46
10
0
% V
% Trp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _