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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERPIND1 All Species: 9.09
Human Site: S408 Identified Species: 20
UniProt: P05546 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05546 NP_000176.2 499 57071 S408 K N Y N L V E S L K L M G I R
Chimpanzee Pan troglodytes XP_001167967 499 57022 S408 K N Y N L V E S L K L M G I R
Rhesus Macaque Macaca mulatta XP_001086464 499 56986 S408 K N Y N L V E S L K S M G I T
Dog Lupus familis XP_855210 414 46891 T329 T L S Y L G I T K I F E E H G
Cat Felis silvestris
Mouse Mus musculus P49182 478 54478 I393 E V L K S M G I T K L F N K N
Rat Rattus norvegicus Q64268 479 54533 I394 E V L K S M G I T K L F N K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518343 283 30581 G198 N A S D S Y D G R T V H G L F
Chicken Gallus gallus P01014 388 43754 M303 S I L M A L G M T D L F S R S
Frog Xenopus laevis Q52L45 377 42679 M292 S Q L A G M G M V D L F N S G
Zebra Danio Brachydanio rerio NP_878300 507 58169 H416 Q N Y D L I E H L K E M G M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787959 393 44064 E307 G M S D A F D E D R A N F E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.9 26.2 N.A. 81.9 82.3 N.A. 26.2 24.8 22.2 51.6 N.A. N.A. N.A. N.A. 28.2
Protein Similarity: 100 99.8 97.3 45.4 N.A. 87.9 88.7 N.A. 35.8 42.8 43 71.7 N.A. N.A. N.A. N.A. 46
P-Site Identity: 100 100 86.6 6.6 N.A. 13.3 13.3 N.A. 6.6 6.6 6.6 53.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 86.6 13.3 N.A. 26.6 26.6 N.A. 33.3 13.3 20 80 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 19 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 28 0 0 19 0 10 19 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 37 10 0 0 10 10 10 10 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 10 37 10 0 10 % F
% Gly: 10 0 0 0 10 10 37 10 0 0 0 0 46 0 28 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % H
% Ile: 0 10 0 0 0 10 10 19 0 10 0 0 0 28 0 % I
% Lys: 28 0 0 19 0 0 0 0 10 55 0 0 0 19 0 % K
% Leu: 0 10 37 0 46 10 0 0 37 0 55 0 0 10 0 % L
% Met: 0 10 0 10 0 28 0 19 0 0 0 37 0 10 0 % M
% Asn: 10 37 0 28 0 0 0 0 0 0 0 10 28 0 19 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 19 % R
% Ser: 19 0 28 0 28 0 0 28 0 0 10 0 10 10 10 % S
% Thr: 10 0 0 0 0 0 0 10 28 10 0 0 0 0 19 % T
% Val: 0 19 0 0 0 28 0 0 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 37 10 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _