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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPIND1
All Species:
14.24
Human Site:
T206
Identified Species:
31.33
UniProt:
P05546
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05546
NP_000176.2
499
57071
T206
H
N
L
F
R
K
L
T
H
R
L
F
R
R
N
Chimpanzee
Pan troglodytes
XP_001167967
499
57022
T206
H
N
L
F
R
K
L
T
H
R
L
F
R
R
N
Rhesus Macaque
Macaca mulatta
XP_001086464
499
56986
T206
H
N
L
F
R
K
L
T
H
R
L
F
R
R
N
Dog
Lupus familis
XP_855210
414
46891
L134
S
Q
D
L
E
L
H
L
R
N
T
L
F
I
D
Cat
Felis silvestris
Mouse
Mus musculus
P49182
478
54478
R198
R
N
F
G
Y
T
L
R
S
V
N
G
L
Y
I
Rat
Rattus norvegicus
Q64268
479
54533
Q199
R
N
F
G
Y
T
L
Q
S
V
N
D
L
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518343
283
30581
Chicken
Gallus gallus
P01014
388
43754
V108
E
I
A
D
K
L
Y
V
D
K
T
F
S
V
L
Frog
Xenopus laevis
Q52L45
377
42679
K97
A
N
R
L
F
G
E
K
T
F
N
F
L
P
N
Zebra Danio
Brachydanio rerio
NP_878300
507
58169
T214
H
K
L
F
R
K
L
T
H
R
L
F
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787959
393
44064
Y112
R
L
Y
G
K
S
G
Y
N
F
V
Q
S
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.9
26.2
N.A.
81.9
82.3
N.A.
26.2
24.8
22.2
51.6
N.A.
N.A.
N.A.
N.A.
28.2
Protein Similarity:
100
99.8
97.3
45.4
N.A.
87.9
88.7
N.A.
35.8
42.8
43
71.7
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
100
0
N.A.
13.3
13.3
N.A.
0
6.6
20
93.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
13.3
13.3
N.A.
0
20
20
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
10
0
0
10
0
0
10
% D
% Glu:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
19
37
10
0
0
0
0
19
0
55
10
10
0
% F
% Gly:
0
0
0
28
0
10
10
0
0
0
0
10
0
0
0
% G
% His:
37
0
0
0
0
0
10
0
37
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
19
% I
% Lys:
0
10
0
0
19
37
0
10
0
10
0
0
0
0
0
% K
% Leu:
0
10
37
19
0
19
55
10
0
0
37
10
28
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
55
0
0
0
0
0
0
10
10
28
0
0
0
46
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
28
0
10
0
37
0
0
10
10
37
0
0
37
37
0
% R
% Ser:
10
0
0
0
0
10
0
0
19
0
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
19
0
37
10
0
19
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
19
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
19
0
10
10
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _