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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPIND1
All Species:
13.33
Human Site:
T374
Identified Species:
29.33
UniProt:
P05546
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05546
NP_000176.2
499
57071
T374
K
T
L
E
A
Q
L
T
P
R
V
V
E
R
W
Chimpanzee
Pan troglodytes
XP_001167967
499
57022
T374
K
T
L
E
A
Q
L
T
P
R
V
V
E
R
W
Rhesus Macaque
Macaca mulatta
XP_001086464
499
56986
T374
K
T
L
E
A
Q
L
T
P
Q
V
V
E
R
W
Dog
Lupus familis
XP_855210
414
46891
W295
K
A
D
T
F
D
R
W
K
K
L
I
T
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P49182
478
54478
R359
L
T
P
Q
V
V
E
R
W
Q
K
S
M
T
N
Rat
Rattus norvegicus
Q64268
479
54533
R360
L
T
P
Q
V
V
E
R
W
Q
K
S
M
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518343
283
30581
A164
A
P
V
G
I
S
A
A
L
S
M
V
S
L
G
Chicken
Gallus gallus
P01014
388
43754
T269
F
D
K
L
R
E
W
T
S
T
N
A
M
A
K
Frog
Xenopus laevis
Q52L45
377
42679
E258
L
S
L
E
K
I
H
E
W
T
E
N
M
M
P
Zebra Danio
Brachydanio rerio
NP_878300
507
58169
S382
R
S
L
E
Q
E
I
S
P
T
L
V
N
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787959
393
44064
K273
Q
S
W
D
A
G
L
K
S
R
Q
V
N
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.9
26.2
N.A.
81.9
82.3
N.A.
26.2
24.8
22.2
51.6
N.A.
N.A.
N.A.
N.A.
28.2
Protein Similarity:
100
99.8
97.3
45.4
N.A.
87.9
88.7
N.A.
35.8
42.8
43
71.7
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
93.3
13.3
N.A.
6.6
6.6
N.A.
6.6
6.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
33.3
N.A.
20
20
N.A.
20
13.3
20
80
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
37
0
10
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
10
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
46
0
19
19
10
0
0
10
0
28
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
0
% I
% Lys:
37
0
10
0
10
0
0
10
10
10
19
0
0
10
10
% K
% Leu:
28
0
46
10
0
0
37
0
10
0
19
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
37
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
19
0
19
% N
% Pro:
0
10
19
0
0
0
0
0
37
0
0
0
0
0
10
% P
% Gln:
10
0
0
19
10
28
0
0
0
28
10
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
10
19
0
28
0
0
0
37
10
% R
% Ser:
0
28
0
0
0
10
0
10
19
10
0
19
10
0
0
% S
% Thr:
0
46
0
10
0
0
0
37
0
28
0
0
10
19
0
% T
% Val:
0
0
10
0
19
19
0
0
0
0
28
55
0
10
0
% V
% Trp:
0
0
10
0
0
0
10
10
28
0
0
0
0
0
37
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _